Complete Genomic Sequence of Human Coronavirus OC43: Molecular Clock Analysis Suggests a Relatively Recent Zoonotic Coronavirus Transmission Event

By L. Vijgen, E. Keyaerts, E. Moës, I. Thoelen, E. Wollants, Philippe Lemey, Anne-Mieke Vandamme, M. Van Ranst. 2005

546 citations recorded by the source corpus.

Subfields: Animal Science and Zoology, Infectious Diseases

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Citations in the corpus

Molecular Evolution of Human Coronavirus Genomes (2016, unknown): “HCoV-OC43 is thought to have shared a common ancestor with BCoV around 120 years ago [87].”
Zoonotic origins of human coronaviruses (2020, background): “When HCoV-OC43 crossed species to infect humans from domestic livestock around 1890, a pandemic of respiratory infection was recorded [68] .”
Coronaviruses post-SARS: Update on replication and pathogenesis (2009, background): “BCoV and HCoV-OC43 are similar and the virus may have crossed from bovine to human hosts approximately 100 years ag”
Structure, Function, and Evolution of Coronavirus Spike Proteins (2016, background): “In contrast, despite the structural similarity between MHV and BCoV S1-NTDs, MHV S1-NTD binds CEACAM1 but not sugar (43, 88).”
Coronavirus Genomics and Bioinformatics Analysis (2010, background): “0) 10 nucleotide substitutions per site per year [30].”
Molecular Epidemiology of Human Coronavirus OC43 Reveals Evolution of Different Genotypes over Time and Recent Emergence of a Novel Genotype due to Natural Recombination (2011, background): “This was followed by genomic studies on two HCoVOC43 strains detected in 2003 and 2004 in Belgium, showing that the Belgium strains were genetically distinct and that HCoV-OC43 could have originated from recent zoonotic transmission (47, 48).”
Evolutionary History of the Closely Related Group 2 Coronaviruses: Porcine Hemagglutinating Encephalomyelitis Virus, Bovine Coronavirus, and Human Coronavirus OC43 (2006, methodology): “2 coronaviruses, as described previously, were used (33).”
Circulation of genetically distinct contemporary human coronavirus OC43 strains (2005, unknown): “This value is consistent with the previously estimated evolutionary rate of the BCoV/HCoV-OC43 pair, and that of other coronaviruses (TGEV and SARS-CoV) (Salemi et al., 2004; Sanchez et al., 1992; Vijgen et al., 2005a) .”
Coronavirus Infections in Children Including COVID-19 (2020, background): “These viruses are believed to have originally derived from bats (NL63, 229E),(17,18) dromedary camels (229E)(19) and cattle (OC43).(20) The origin of HCoV-HKU1 remains unknown.”
Hosts and Sources of Endemic Human Coronaviruses (2018, background): “Only forHCoV-OC43,which belongs to the speciesBetacoronavirus 1 (BetaCoV 1), a zoonotic acquisition from ungulate livestock is widely accepted (de Groot et al., 2012a, b; Vijgen et al., 2005, 2006).”
Human Coronavirus HKU1 Spike Protein Uses O-Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme (2015, background): “, hCoV-OC43 and its proposed zoonotic ancestor, bovine coronavirus (BCoV) (25).”