Coronaviruses post-SARS: Update on replication and pathogenesis

By S. Perlman, Jason Netland. Nature Reviews Microbiology, 2009

1,679 citations recorded by the source corpus.

Although coronaviruses were first identified nearly 60 years ago, they only received notoriety in 2003 when one of their members was identified as the aetiological agent of severe acute respiratory syndrome. Previously these viruses were known to be important agents of respiratory and enteric infections of domestic and companion animals and to cause approximately 15% of all cases of the common cold. This Review focuses on recent advances in our understanding of the mechanisms of coronavirus replication, interactions with the host immune response and disease pathogenesis. It also highlights the recent identification of numerous novel coronaviruses and the propensity of this virus family to cross species barriers.

Subfields: Infectious Diseases, Neurology

View Paper: https://www.semanticscholar.org/paper/7b8fe6524b0972358faf10ef57a0e9bf165e6f11

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In Infectious Diseases

1. Fang Li
2. J. Millet
3. Gary R. Whittaker
4. Ralph S. Baric
5. Yu Chen
6. Qianyun Liu
7. D. Guo
8. S. Perlman

In Neurology

1. Fang Li
2. Ralph S. Baric
3. Andrew G. Harrison
4. Tao Lin
5. Penghua Wang
6. Yu Chen
7. Qianyun Liu
8. D. Guo

Citations in the corpus

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• Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry (2019, background): “77 Coronaviruses are a family of large, positive-stranded, and enveloped RNA 78 viruses (11, 12).”
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