Two-photon calcium imaging reveals an odor-evoked map of activity in the fly brain.

By Jing W. Wang, A. Wong, J. Flores, Leslie B. Vosshall, R. Axel. Cell, 2003

814 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Endocrine and Autonomic Systems, Sensory Systems

View Paper: https://www.semanticscholar.org/paper/f8e285e51a259ef0f94d69df2765a25132ca9547

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In Cellular and Molecular Neuroscience

In Endocrine and Autonomic Systems

In Sensory Systems

Citations in the corpus

Motor control in a Drosophila taste circuit (2009, neutral): “(Bloomington stock center); UAS > CD2,y+ > -mCD8::GFP (Wong et al., 2002); UAS-G-CaMP ( Wang et al., 2003 ); Or83b-LexA::VP16 (Lai and Lee, 2006);”
Drosophila α/β Mushroom Body Neurons Form a Branch-Specific, Long-Term Cellular Memory Trace after Spaced Olfactory Conditioning (2006, positive): “Flies carrying Uas transgenes containing Drosophila the Creb2-b repressor coding region (Uas-dCreb2-b, see below) or G-CaMP (Uas-G-CaMP, Wang et al., 2003; Wang et al., 2004) were employed along with the c739-Gal4 driver (c739-Gal4 flies were from K. Kaiser, Division of Molecular Genetics,…”
A Complete Developmental Sequence of a Drosophila Neuronal Lineage as Revealed by Twin-Spot MARCM (2010, background): “Following the trajectories of PNs that connect with distinct ORNs has started to unravel how different olfactory inputs might be processed differentially to govern diverse organismal behaviors [35].”
The molecular basis of odor coding in the Drosophila antenna. (2004, background): “Stimuli were and activate larger numbers of glomeruli (Ng et al., 2002; presented by placing the tip of the pipette through a hole in a Wang et al., 2003).”
Non-Canonical Odor Coding in the Mosquito (2020, background): “…in insect olfactory systems, and the convergence onto discrete glomeruli is hypothesized to permit the brain to utilize combinatorial coding and parse which subpopulation of olfactory neurons is activated by a given odorant (Bisch-Knaden et al., 2018; Semmelhack and Wang, 2009; Wang et al., 2003).”
Testing odor response stereotypy in the Drosophila mushroom body. (2008, background): “Imaging and electrophysiological studies in both the antennal lobe and olfactory bulb have shown reproducible odor responses across animals (Belluscio and Katz, 2001; de Bruyne et al., 2001; Hallem et al., 2004; Meister and Bonhoeffer, 2001; Ng et al., 2002; Rubin and Katz, 1999; Uchida et al., 2000”
Stereotyped Odor-Evoked Activity in the Mushroom Body of Drosophila Revealed by Green Fluorescent Protein-Based Ca2+ Imaging (2004, methodology): “…of ORN projections give rise to topographic activation patterns of glomeruli that are both odor specific and conserved in different individuals (Stocker et al., 1983; Rodrigues, 1988; Johnson et al., 1998; Galizia et al., 1999; Rubin and Katz, 1999; Wachowiak and Cohen, 2001; Wang et al., 2003).”
Organization of antennal lobe‐associated neurons in adult Drosophila melanogaster brain (2012, background): “…studies in insects and vertebrates (Galizia et al., 1999; Sachse et al., 1999; Rubin and Katz, 1999; Belluscio and Katz, 2001; Uchida et al., 2000; Wang et al., 2003), and electrophysiological studies (Laurent, 1999) have shown #Present address: Career-Path Promotion Unit for Young Life…”
Olfactory information processing in Drosophila. (2009, neutral): “First, there is a technical issue: the calcium signal recorded using the GCaMP reporter [ 50 ] has a complex relationship with projection neuron spiking and is likely to miss low projection neuron spike rates [61].”
Comprehensive Maps of Drosophila Higher Olfactory Centers: Spatially Segregated Fruit and Pheromone Representation (2007, positive): “While there is experimental support for this labeled-line hypothesis (Ng et al., 2002; Wang et al., 2003), significant broadening of PN tuning profiles compared with their corresponding ORNs has also been reported (Wilson et al., 2004).”
Or83b encodes a broadly expressed odorant receptor essential for Drosophila olfaction. (2004, methodology): “The Or83b-Gal4 transgenefamily is undergoing rapid evolutionary change with virwas constructed as previously described (Wang et al., 2003).”