Drosophila α/β Mushroom Body Neurons Form a Branch-Specific, Long-Term Cellular Memory Trace after Spaced Olfactory Conditioning

By Dinghui Yu, D. Akalal, Ronald L. Davis. 2006

251 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Immunology, Insect Science

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Citations in the corpus

Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila (2014, background): “…our results indicate that circuits in the α lobe play key roles in long-term aversive and appetitive memory (Figure 10) (Pascual and Preat, 2001; Isabel et al., 2004; Yu et al., 2006; Blum et al., 2009; Sejourne et al., 2011; Cervantes-Sandoval et al., 2013; Pai et al., 2013; Placais et al., 2013).”
System-like consolidation of olfactory memories in Drosophila (2013, methodology): “This enhancement persists through 24 h and requires normal protein synthesis, spaced conditioning, the activity of the transcription factor Creb, and the normal function of 26 different LTM genes (Yu et al., 2006; Akalal et al., 2011).”
Are mushroom bodies cerebellum-like structures? (2011, background): “…in the Drosophilamushroom bodies through rutabaga adenylyl cyclase activation potentiates Ca2þ influx in Kenyon cells in response to stimulation (Yu et al., 2006; Tomchik and Davis, 2009; Akalal et al., 2010), although a causal link to LTP-like synaptic plasticity in Kenyon cells remains to be…”
The Long-Term Memory Trace Formed in the Drosophilaα/β Mushroom Body Neurons is abolished in Long-Term Memory Mutants (2011, methodology): “Olfactory learning was assayed using an olfactory classical conditioning procedure that allows the performance gains occurring from the pairing of a single odor with electric shock to be measured relative to naive flies (Yu et al., 2006).”
Olfactory information processing in Drosophila. (2009, unknown): “that associative learning is accompanied by an increase in calcium levels in Kenyon cell axons, suggesting that learning alters the probability of synaptic vesicle release from Kenyon cells [ 111 ].”
Spaced Training Forms Complementary Long-Term Memories of Opposite Valence in Drosophila (2019, unknown): “, 2016) via dopamine receptor directed cAMPdependent plasticity (Yu et al., 2006; Kim et al., 2007; Tomchik and Davis, 2009; Qin et al., 2012; Zhang and Roman, 2013; Boto et al., 2014; Hige et al., 2015).”
A neural circuit mechanism integrating motivational state with memory expression in Drosophila (2009, background): “424 Cell 139, 416–427, October 16, 2009 ª2009 Elsevier Inc. Preat, 2001; Yu et al., 2005, 2006), other DA neurons in PPL1 that innervate the a lobe (like those labeled in MBGAL80;krasavietz, Figures 5C and S4) may provide reinforcement.”
Memory Engram Cells Have Come of Age. (2015, unknown): “…learning pathway, such as those in the antennal lobes and mushroom bodies, changed their responses selectively towards the odor used in the training, suggesting that cue-specific memory traces were formed within these cell populations as a result of learning (Liu and Davis, 2009; Yu et al., 2006).”