Lipid signalling in disease

By M. Wymann, R. Schneiter. Nature reviews. Molecular cell biology, 2008

1,270 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/f85b7c669d7a7e680553fa2d9ab78ba533077f0c

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Citations in the corpus

Host-derived lipids and oxylipins are crucial signals in modulating mycotoxin production by fungi (2009, background): “Reminiscent of the apparent exacerbation of fungal infections by specific plant 9-oxylipins described in this review, in certain cases, mammalian eicosanoids contribute to normal invasion of pathogenic microbes and disease progression (Noverr et al., 2003; Wymann and Schneiter, 2008).”
Cellular Fatty Acid Metabolism and Cancer (2013, background): “FAs derived from lipolysis can also serve as precursors for important signaling lipids (see Wymann and Schneiter, 2008).”
Chronic Inflammation in Obesity and the Metabolic Syndrome (2010, background): “Ceramide may also activate protein phosphatase 2A, which inactivates PKB/Akt and attenuates insulin response, contributing to insulin resistance [55].”
Dysregulated pH: a perfect storm for cancer progression (2011, background): “The functional significance of pH-dependent histidine switches for phosphoinositide binding remains relatively unexplored but could have an important role in pH-regulated metastasis, in which oncogenes drive the synthesis of particular phosphoinositides and the activation of phosphoinositide-binding”
Morbidity and mortality associated with obesity. (2017, background): “These are incorporated in oncogenic signaling lipids that in-turn drives cancer pathogenicity (74).”
Subcellular targeting strategies for drug design and delivery (2010, background): “These lipids play an important part in cell polarity, migration and in pathological condition”
Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development (2013, background): “PGH2 can be converted into additional prostaglandins, including prostaglandin E2 (PGE2), prostacyclin and thromboxanes (Wymann and Schneiter, 2008).”