Endocytic mechanisms for targeted drug delivery.

By Lisa Bareford, P. Swaan. Advanced Drug Delivery Reviews, 2007

1,006 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/f7473ec9fef2698f46c6a0cd93f8a0c4ad34b327

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. O. Farokhzad
2. P. Couvreur
3. H. Hillaireau

In Molecular Biology

1. N. Bertrand
2. N. Kamaly
3. Xiaoyang Xu
4. Jun Wu
5. O. Farokhzad
6. Phatsapong Yingchoncharoen
7. P. Couvreur
8. Jerry S H Lee

In Physiology

1. Phatsapong Yingchoncharoen
2. O. Farokhzad
3. N. Bertrand
4. S. Stern
5. D. Richardson
6. D. Kalinowski
7. P. Adiseshaiah
8. A. Swami

Citations in the corpus

• Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity (2012, background): “tor (EGFR)) is a well understood pathway [12,16].”
• Nanocarriers’ entry into the cell: relevance to drug delivery (2009, background): “Ligands known to be internalized by CvME include folic acid, albumin and cholesterol [81] (see below).”
• Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging (2009, background): “Once a cell-specific NP has bound to the membrane of its target, it is typically taken up by the cell through receptor-mediated endocytosis, where it is trafficked intracellularly via endosomal compartments for processing and destructions through acidification of the endosomes [39].”
• Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come (2016, background): “The vesicle then enters into the cytoplasm, where it fuses with an early or sorting endosome (Bareford and Swaan, 2007).”
• Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. (2014, background): “Evidently, NP intracellular trafficking is complex [162] and receptor-mediated internalization can qualitatively affect the vesicular transport [163, 164].”
• Treating metastatic cancer with nanotechnology (2011, background): “This type of endocytosis can be triggered by the protein transferrin or ligands for glycosylated receptor”
• Magnetic nanoparticles in MR imaging and drug delivery. (2008, background): “Although cleavage from MNP carriers under the hostile environment of the lysosomesmay be suitable for some stable therapeutics [154], the effectiveness of other compounds, such as protein/peptides and oligonucleotides, may be severely compromised.”
• Interactions of nanomaterials and biological systems: implications to personalized nanomedicine (2012, background): “mediated endocytosis (RME) are typically destined for lysosomal degradation; whereas, clathrin-independent RME internalization leads to endosomal accumulation and sorting to a nondegradative path [116].”
• Strategies in the design of nanoparticles for therapeutic applications (2010, background): “For example, engineered nanoparticles internalized through clathrin-mediated endocytosis are destined for a lysosomal compartment, whereas those internalized through a caveolin-mediated process are no”