Enhancement of gastrointestinal absorption of quercetin by solid lipid nanoparticles.

By Houli Li, Xiaobin B. Zhao, Yukun Ma, G. Zhai, Lingbing Li, H. Lou. Journal of Controlled Release, 2009

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Nanoscience and nanotechnologies in food industries: opportunities and research trends (2014, background): “…as an oral delivery carrier to enhance the gastrointestinal absorption and, thus, the bioavailability of quercetin, a natural healthcare product Li et al. (2008b) Nanotea, from Chinese industry is a nano- selenium-enriched tea, which is claimed to enhance selenium uptake and…”
Nanotechnology in agro-food: From field to plate (2015, background): “Additionally, encapsulation also aids in controlled release of active ingredients wherein gastrointestinal retention time can be prolonged and the site of release of active ingredient can be adjusted according to the need (Medina, Santos-Martinez, Radomski, Corrigan, & Radomski, 2007; Krasaekoopt, B”
Strategies to Address Low Drug Solubility in Discovery and Development (2013, methodology): “More stable systems have been described in which solid SEDDS are prepared by dissolving drug in a melt containing SEDDS excipients and high-molecularweight PEG or poloxamer (to promote solidification) followed by hot filling into capsules and cooling (Li et al., 2009b; Shah and Serajuddin, 2012).”
Recent Advances in Lipid Nanoparticle Formulations with Solid Matrix for Oral Drug Delivery (2011, methodology): “Another study has investigated the influence of different Quercetin Enhancement of GI absorption SLN Emulsification and lowtemperature solidification ( 106 )”