The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis.

By I. Conboy, T. Rando. Developmental Cell, 2002

921 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/f53d7062880df5677012f6c6d42e69b7ea117a72

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

In Surgery

Citations in the corpus

Satellite cells and the muscle stem cell niche. (2013, background): “Such an activation signal from myofibers is probably amplified by the expression of both Notch receptors and Delta ligands on satellite cells, functioning in autocrine and juxtacrine fashion (108, 280).”
Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells (2006, background): “Most hindlimb muscles, usually used as a source of satellite cells (Seale et al., 2000; Conboy and Rando, 2002), and some forelimb and trunk muscles are negative for Pax3.”
The aged niche disrupts muscle stem cell quiescence (2012, background): “That aged SCs break quiescence under homeostatic conditions was surprising considering their proliferative disadvantage in high mitogen regenerative contexts 39 .”
Rejuvenation of aged progenitor cells by exposure to a young systemic environment (2005, background): “A decline in skeletal muscle stem cell (satellite cell) activity due to a loss of Notch signalling results in impaired regeneration of aged muscl”
Muscle satellite cells adopt divergent fates (2004, background): “, 1999), components of which are expressed by satellite cells (Conboy and Rando, 2002).”
Cellular and molecular regulation of muscle regeneration. (2004, background): “In favor of satellite cell asymmetric division is the recent observation by Conboy and Rando (70) that Numb, a plasma membrane-associated cytoplasmic protein, is asymmetrically segregated within dividing satellite cells in vitro.”
The Skeletal Muscle Satellite Cell: The Stem Cell That Came in From the Cold (2006, background): “…54(11): 1177–1191, 2006 Journal of Histochemistry & Cytochemistry http://www.jhc.org demonstration that the multinucleated skeletal myofiber, the contractile unit of muscle, is formed by the fusion of large numbers of mononucleate myoblasts (Cooper and Konigsberg 1961; Stockdale and Holtzer 1961).”
Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation (2007, neutral): “This unique property of stem cells has been exploited to identify mouse muscle satellite cells [80] and could possibly be used to identify MSCs in vivo and to study their division.”