Differential timing and control of noncrossover and crossover recombination during meiosis.

By T. Allers, M. Lichten. Cell, 2001

692 citations recorded by the source corpus.

Subfields: Cell Biology, Materials Chemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f4289440a8fe0b859546e170210ef3c4c491fcb8

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In Cell Biology

1. N. Hunter
2. Rodney Rothstein
3. M. Jasin
4. L. Symington

In Materials Chemistry

1. N. Hunter
2. George P. Patrinos
3. L. Symington

In Molecular Biology

1. N. Hunter
2. L. Symington
3. H. Klein
4. P. Sung
5. G. Börner
6. M. Jasin
7. Rodney Rothstein
8. Xiaolan Zhao

Citations in the corpus

• Gene conversion: mechanisms, evolution and human disease (2007, background): “At least in yeast, the control of crossover and non-crossover recombination is differentially timed during meiosi”
• Crossover/noncrossover differentiation, synaptonemal complex formation, and regulatory surveillance at the leptotene/zygotene transition of meiosis. (2004, background): “Subsequent studies have shown that the long-lived dHJs seen during wild-type meiosis are precursors specifically of CRs (Allers and Lichten, 2001) and that crossover control occurs concomitant with or prior to formation of SEIs (Hunter and Kleckner, 2001).”
• Recombination proteins in yeast. (2004, background): “However, recent studies suggest crossover and noncrossover products are generated from different intermediates in meiotic recombination (7).”
• The Bloom's syndrome helicase suppresses crossing over during homologous recombination (2003, background): “The formation of crossover and non-crossover products during homologous recombination has been proposed to occur through the use of independent pathways, as opposed to two alternative outcomes of a single reactio”
• Role of RAD52 Epistasis Group Genes in Homologous Recombination and Double-Strand Break Repair (2002, background): “Kinetic studies suggest that SEIs arise before dHJ intermediates and could be precursors to them or could be processed independently to form noncrossover products (11, 144).”
• Mechanism of homologous recombination: mediators and helicases take on regulatory functions (2006, background): “SDSA probably also accounts for those meiotic DSBR events that do not give rise to crossover”
• Meiotic Recombination: The Essence of Heredity. (2015, background): “Along the crossover pathway, SEIs give rise to dHJs, which must be resolved exclusively into crossovers, in contrast to the equal mixture of crossovers and noncrossovers originally envisioned by the DSBR model (Allers and Lichten 2001a; Clyne et al. 2003; Zakharyevich et al. 2012).”
• Repair of strand breaks by homologous recombination. (2013, background): “…of the other DNA end by the D loop to form a dHJ; although originally postulated to be resolved as either a CO or NCO (Orr-Weaver and Szostak 1983), dHJ resolution appears to be biased to the formation of COs (Allers and Lichten 2001) by the combined activity of a MutL complex and Exo1 (Fig.”
• Homologous recombination and its regulation (2012, background): “During meiosis, crossovers are formed by resolution of dHJs via the DSBR mechanism, while non-crossovers are primarily produced via SDSA mechanism (10,11).”