Role of RAD52 Epistasis Group Genes in Homologous Recombination and Double-Strand Break Repair

By L. Symington. Microbiology and Molecular Biology Reviews, 2002

1,047 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/b48f4d752a792695ea8e5c0a14454d759ef88252

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Citations in the corpus

Gene targeting in filamentous fungi: the benefits of impaired repair (2007, background): “The RAD52 gene group that comprises several components of the cellular HR machinery has been characterised at the molecular level (Symington 2002), mainly based on research in the baker’s yeast S. cerevisiae in which HR is extremely efficient and therefore the principal way of foreign DNA…”
Autophagy suppresses tumor progression by limiting chromosomal instability. (2007, background): “Analogously, mutations in genes critical for DNA repair create sensitivity to DNA damage but enhance tumorigenesis by increasing the mutation rate (Symington 2002).”
Inaugural Article: Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules (2009, neutral): “The first step requires resection of the broken duplex DNA by a helicase and/or nuclease to produce a region of 3 -terminated single-strand DNA (ssDNA) at the ends of the break (1, 4).”
Recombination proteins in yeast. (2004, background): “cerevisiae results in severe defects in gene conversion, SSA, recombination between inverted repeats, and formation of survivors in the absence of telomerase (202).”
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double strand break ends (2008, neutral): “The strand exchange protein Rad51 assembles a nucleofilament at 30 ssDNA tails that carries out a search for homologous sequences and promotes strand invasion (reviewed in San Filippo et al., 2008; Symington, 2002).”