Repair of strand breaks by homologous recombination.

By M. Jasin, Rodney Rothstein. Cold Spring Harbor Perspectives in Biology, 2013

863 citations recorded by the source corpus.

Subfields: Civil and Structural Engineering, Plant Science

View Paper: https://www.semanticscholar.org/paper/8d64b8974cd75e46b4d675705e177dd69da00289

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Plant Science

1. Feng Zhang
2. Richard D. Newcomb
3. Eugene V. Koonin
4. M. Jasin

Citations in the corpus

• RNA-guided DNA insertion with CRISPR-associated transposases (2019, background): “Although it is possible to achieve precise integration of new DNA following Cas9 cleavage either through homologous recombination (10) or nonhomologous end-joining (11, 12), these processes are inefficient and vary greatly depending on cell type.”
• Homologous recombination and human health: the roles of BRCA1, BRCA2 and associated proteins (2015, background): “More complex pathways involve Holliday junction resolution or dissolution (Jasin and Rothstein 2013; see also Bizard and Hickson 2014; Wyatt and West 2014).”
• Targeted Mutagenesis, Precise Gene Editing, and Site-Specific Gene Insertion in Maize Using Cas9 and Guide RNA[OPEN] (2015, background): “DSBs in eukaryotic cells can be repaired using two different pathways—nonhomologous end joining (NHEJ) and HDR (Roth and Wilson, 1986; Moore and Haber, 1996; Puchta et al., 1996; Jasin and Rothstein, 2013).”
• p53 in the DNA damage repair process (2016, background): “DNA DSBs are repaired by two pathways, depending on the stage of the cell cycle: NHEJ is active throughout the cell cycle, but especially important in G1 (Deriano and Roth 2013) and HR, which is most active during late S and G2 (Jasin and Rothstein 2013).”
• The potential for the use of gene drives for pest control in New Zealand: a perspective (2018, background): “Organisms try to repair such cuts by homology-directed DNA repair (HDR), a process whereby an organism with a double-stranded break in its DNA will try and repair that break by copying any similar sequence it can find in the cell (Jasin & Rothstein 2013).”