Matrix metalloproteinases: biologic activity and clinical implications.

By Amy R. Nelson, B. Fingleton, M. Rothenberg, L. Matrisian. Journal of Clinical Oncology, 2000

1,568 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/f12578f6f33acb1e95d86d814db8fe7479bd7253

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Citations in the corpus

Angiogenesis in Cancer (2006, neutral): “Naoyo Nishida1, 2 Hirohisa Yano1 Takashi Nishida3 Toshiharu Kamura2 Masamichi Kojiro1 Departments of 1Pathology and 2Obstetrics and Gynecology and Research Center of Innovative Cancer Therapy of the 21 Century COE Program for Medical Science, Kurume University School of Medicine, Fukuoka, Japan; 3Hi”
Matrix-degrading Metalloproteinases in Photoaging (2009, neutral): “MMP GENE EXPRESSION IN NON-IRRADIATED AND UV-IRRADIATED HUMAN SKIN IN VIVO MMPs comprise a family of zinc-containing proteinases that are responsible for degrading ECM proteins, which form skin dermal connective tissue (Nelson et al., 2000; Sternlicht and Werb, 2001).”
Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype. (2008, background): “Increased MMPs such as MMP-2 or MMP-9 correlates with the increased cell invasion and metastasis (47).”
Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. (2008, background): “MT1-MMP is known to be able to activate MMP2 and MMP13, both of which are associated with tumor invasion (d’Ortho et al., 1997; English et al., 2001; Leeman et al., 2002; Nelson et al., 2000).”
Inflammation after Intracerebral Hemorrhage (2007, background): “To date, approximately 24 different vertebrate MMPs have been identified, of which 23 are found in humans (Gueders et al, 2006; Nelson et al, 2000).”
Oxidative stress, inflammation, and cancer: how are they linked? (2010, background): “MMPs are capable of cleaving most components of the basement membrane and extracellular matrix [201].”
How matrix metalloproteinases regulate cell behavior. (2001, background): “Thus like the many proteins they modify, the MMPs influence diverse physiologic and pathologic processes, including aspects of embryonic development, tissue morphogenesis, wound repair, inflammatory diseases, and cancer (Nelson et al. 2000, Sternlicht et al. 2001).”
Matrix metalloproteinases in neuroinflammation (2002, background): “Control of the inducible MMPs occurs at multiple sites, including activator protein-1 (AP-1), nuclear factor- B (NF- B), and PEA-3 (Ets-1) sites (Nelson et al., 2000) (Fig.”
Reactive oxygen species in tumor progression. (2005, background): “Increased activation of MMPs correlates with increased cell motility, tumor invasion and metastasis, since MMPs are capable of cleaving most components of the basement membrane and extracellular matrix (54).”