Tight junctions of the blood-brain barrier: development, composition and regulation.

By H. Wolburg, A. Lippoldt. Vascular pharmacology, 2002

1,180 citations recorded by the source corpus.

Subfields: Molecular Biology, Neurology, Oncology

View Paper: https://www.semanticscholar.org/paper/efdef2765d0e178c8a324e42db8396e4d90c7e2c

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Citations in the corpus

Permeability Studies on In Vitro Blood–Brain Barrier Models: Physiology, Pathology, and Pharmacology (2005, background): “The most important integral membrane TJ proteins include occludin, claudin-1 and -5, and junctional adhesion molecules (JAMs) (for review, see Krizbai and Deli, 2003; Matter and Balda, 2003b; Wolburg and Lippoldt, 2002).”
Structure and function of the blood-brain barrier. (2010, background): “The tight junctions consist of a further complex of proteins spanning the intercellular cleft (occludin and claudins), and junctional adhesion molecules (JAMs) (Wolburg and Lippoldt, 2002; Wolburg et al., 2009) (Fig.”
The blood-brain barrier: an engineering perspective (2013, background): “Morphologically, astrocytes are usually star shaped with many processes or protrusions emanating from the cell body, with an overall diameter of about 140 μm in the human brain (Oberheim et al., 2009).”
A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity (2020, background): “Abbreviations BBB: Blood–brain barrier; CNS: Central nervous system; CSF: Cerebrospinal fluid; BCB: Blood–CSF barrier; ISF: Interstitial fluid; TJs: Tight junctions; P-gp: P-glycoprotein; BCRP: Breast cancer resistance protein; OATP: Organic anion transporting polypeptide; CYP 450: Cytochrome P450; ”
Blood‐brain barrier‐specific properties of a human adult brain endothelial cell line (2005, background): “This selectivity resides in specialized features unique to CNS endothelia (1), including expression of tight intercellular junctions that markedly limit paracellular permeability plus a unique pattern of receptors, transporters, and nonselective drug export pumps that protect the CNS from a very lar”
Western Diet Consumption and Cognitive Impairment: Links to Hippocampal Dysfunction and Obesity (2010, background): “2a), which are considered important in permeability restriction [99].”
The Blood-Brain Barrier/Neurovascular Unit in Health and Disease (2005, background): “…by the presence of a junctional complex that includes adherens junctions (AJ) (Schulze and Firth, 1993), TJ (Kniesel and Wolburg, 2000; Wolburg and Lippoldt, 2002; Vorbrodt and Dobrogowska, 2003), and possibly gap junctions (Tao-Cheng et al., 1987; Braet et al., 2001; Kojima et al.,…”
Retinal vascular image analysis as a potential screening tool for cerebrovascular disease: a rationale based on homology between cerebral and retinal microvasculatures (2005, background): “Transmembrane proteins are often found in conjunction with submembranous tight junctionassociated proteins [zonula occludens (ZO-1, ZO-2, ZO3)] (Stevenson et al. 1986; Watson et al. 1991; Wolburg & Lippoldt, 2002).”
Blood–brain Barrier: Structural Components and Function Under Physiologic and Pathologic Conditions (2006, background): “Occludin Occludin is a 65-kDa protein highly expressed in BMVEC, and it is detected consistently along the cell margins (Wolburg and Lippoldt 2002; Hawkins and Davis 2005).”
Regulation of retinal blood flow in health and disease. (2008, background): “, 1987) and through release of humoral factors (see (Wolburg and Lippoldt, 2002).”