Permeability Studies on In Vitro Blood–Brain Barrier Models: Physiology, Pathology, and Pharmacology

By M. Deli, C. Ábrahám, Y. Kataoka, M. Niwa. Cellular and molecular neurobiology, 2005

645 citations recorded by the source corpus.

Subfields: Neurology, Oncology

View Paper: https://www.semanticscholar.org/paper/a24ff420a17cc04938c8382e1510a2477c4ab67b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Neurology

1. William A. Banks
2. Amanda F. Levy
3. Mao Ye
4. Peter C. Searson
5. Jeffrey D. Rothstein
6. D. Bergles
7. Andrew D. Wong

In Oncology

1. Amanda F. Levy
2. Mao Ye
3. Peter C. Searson
4. Jeffrey D. Rothstein
5. D. Bergles
6. Andrew D. Wong

Citations in the corpus

• The blood-brain barrier: an engineering perspective (2013, methodology): “TEER measurements have been widely used to characterize tight junctions (Madara, 1998; Franke et al., 1999; Gumbleton and Audus, 2001; Reichel et al., 2003; Deli et al., 2005; Shen et al., 2011).”
• A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes. (2009, neutral): “A great number of currently used in vitro BBB model is composed of coculture of brain endothelial cells with astrocytes (Deli et al., 2005; Deli, 2007; Cecchelli et al., 2007).”
• From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery (2016, background): “1α,25-dihydroxyvitam D3 enhances cerebral clearance of human amyloid-β peptide(1-40) from mouse brain across the blood–brain barrier.”
• CNS immune privilege: hiding in plain sight (2006, background): “In addition, activation of the peripheral immune system can lead to BBB leakiness caused by systemic production of inflammatory mediators [TNF, nitric oxide (NO)] and can lead to transmigration of activated macrophages and dendritic cells (competent APCs) across the BBB (25, 57, 58).”
• TEER measurement techniques for in vitro barrier model systems (2015, positive): “Although cerebral endothelial cells are the principal components of the BBB, there is increasing evidence of other cell types such as glial cells, pericytes, and neurons playing important regulatory roles in the induction and maintenance of the BBB, and these can be included to develop more complex ”