Histone methylation versus histone acetylation: new insights into epigenetic regulation.

By J. Rice, C. D. Allis. Current Opinion in Cell Biology, 2001

728 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/eda4a55437da04374949fc6e54f664e9151c14eb

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

Citations in the corpus

How the ubiquitin–proteasome system controls transcription (2003, background): “— histone H3 methylation, in turn, is required for telomeric-gene silencin”
Partitioning and plasticity of repressive histone methylation states in mammalian chromatin. (2003, neutral): “Bohrgasse 7 (Rice and Allis, 2001; Zhang and Reinberg, 2001; KouzarA-1030 Vienna ides, 2002).”
Histone acetylation: a switch between repressive and permissive chromatin (2002, background): “During the past 2 years, several histone methyltransferases (HMT) that function as epigenetic repressors have been characterized (Rice and Allis, 2001; Zhang and Reinberg, 2001).”
MLL translocations, histone modifications and leukaemia stem-cell development (2007, background): “Chromatin structure may be responsible for 'cellular memory' that persists through cell division, and is thought to be a major form of epigenetic regulation of gene expressio”
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. (2004, background): “…histone methylation has also emerged as a form of post- in the 1960s when Paik and colleagues first reported translational modification that significantly impacts an enzyme that can demethylate free mono- and dichromatin structure (Rice and Allis, 2001; Zhang and N-methyllysine (Kim et al., 1964).”
Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects. (2002, background): “that collectively influence packaging and gene regula- shows that the bulk of the H3-mLys9 is present in the pericentric heterochromatin and in a banded pattern on tion (Rice and Allis, 2001; Strahl and Allis, 2000; Turner, 2000).”
Post-translational modifications in proteins: resources, tools and prediction methods (2021, background): “Recent studies have shown that methylation is associated with fine tuning of various biological processes ranging from transcriptional regulation to epigenetic silencing via heterochromatin assembly (77).”
Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae. (2001, background): “These observations show that H3 Lys9 methylation plays an epigenetic role in establishing silencing in both heterochromatic and euchromatic regions (Jenuwein 2001; Jenuwein and Allis 2001; Rice and Allis 2001).”
Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component (2002, neutral): “jpg" NDATA ITEM> ]> Post-translational modification of histone tails is thought to modulate higher-order chromatin structur”
The human β‐globin locus control region (2002, background): “In this respect the LCR could be involved in regulating chromatin structure beyond the formation of a general DNase I-sensitive domain, for example by regulating the modification of histone tails (methylation, acetylation, phosphorylation) [29].”