How the ubiquitin–proteasome system controls transcription

By Masafumi Muratani, W. Tansey. Nature reviews. Molecular cell biology, 2003

850 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/8cc7138d7376ebafbf173487b0bd7144bcf95de3

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Ivan Dikic
2. Hyungwon Choi
3. Vladimir N Uversky
4. S. Lecker
5. A. Goldberg
6. A. Gingras
7. Predrag Radivojac
8. W. Mitch

In Oncology

1. Ivan Dikic
2. M. Hung
3. A. Goldberg
4. Binhua P. Zhou
5. G. Gill

Citations in the corpus

• Nuclear retinoid receptors and the transcription of retinoid-target genes. (2004, background): “Finally, the ubiquitin–proteasome system also targets histones and other coregulators (Wang et al., 2002; Yan et al., 2003), therefore increasing the complexity of retinoid-dependent transcriptional control (Muratani and Tansey, 2003).”
• Protein degradation by the ubiquitin-proteasome pathway in normal and disease states. (2006, background): “Regulation of Gene Transcription Ub conjugation affects transcription by multiple mechanisms (11).”
• Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transition (2004, background): “We reasoned that Snail might be tightly regulated by the ubiquitin-proteasome pathwa”
• Ubiquitylation and cell signaling (2005, background): “More details on Ub networks during transcription are found in a recent review (Muratani and Tansey, 2003).”
• Identification, Analysis and Prediction of Protein Ubiquitination Sites (2010, methodology): “We demonstrated the utility of UbPred by: (1) predicting precise Ub sites in a dataset of Rsp5 ubiquitin ligase substrates; (2) establishing the correlation between ubiquitination and protein half life; (3) identifying functional categories of yeast and human proteins that are likely to be regulated”
• SUMO and ubiquitin in the nucleus: different functions, similar mechanisms? (2004, background): “Posttranslational modification by ubiquitin is an important regulator of transcription factor activity (Conaway et al. 2002; Muratani and Tansey 2003).”
• SAINTexpress: improvements and additional features in Significance Analysis of Interactome software (2013, background): “…disassembly, SWI/SNF complex, BAF complex, and proteasome core complex, indicating that the interactions that benefited from functionally relevant GO terms related to transcription regulation, for which histone acetyltransferases (HATs) and HDACs are obviously critical regulators [9, 10].”