Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component
By C. Maison, Delphine Bailly, A. Peters, J. Quivy, D. Roche, A. Taddei, M. Lachner, T. Jenuwein, G. Almouzni. Nature Genetics, 2002
687 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/642acf6108723d6e1c177ffc0aef7ffedd53a384
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In Molecular Biology
- T. Jenuwein
- C. D. Allis
- M. Lachner
- G. Almouzni
- C. Maison
- R. Martienssen
- Roderick J. O’Sullivan
- Y. Shinkai
Citations in the corpus
- Epigenetic inheritance during the cell cycle (2009, background): “As in fission yeast, mouse pericentric heterochromatin is enriched in HP1 proteins, the binding of which is dependent on H3K9me3 as well as an unidentified structural RNA componen”
- The role of RNA interference in heterochromatic silencing (2004, background): “Nonetheless, the localization of H3mK9 and HP1 to pericentromeric heterochromatin in mouse is abolished by RNase treatmen”
- G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. (2002, background): “3C), which is much greater than the 50% loss of H3-K9 methylation in Suv39h mutant cells (Maison et al. 2002).”
- Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres (2010, background): “Telomere repeat-containing RNAs (TERRA) appear to affect telomere structure and replication (34), and centromeric RNA is important for pericentric heterochromatin formation (36).”
- DNA hypomethylation and human diseases. (2007, background): “In a mouse cell system the organisation into heterochromatin of pericentric repeats has been shown to involve an RNA component binding to the heterochromatic protein HP1 [164].”
- How do lncRNAs regulate transcription? (2017, background): “In 2011, Maison and colleagues (87) reported that strand-specific centromeric RNAs (transcribed in the forward direction) colocalize with HP1 in mouse cells.”
- Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. (2005, background): “An RNA component seems to be involved in heterochromatin formation in mammalian cells, but the specific nature of this RNA component and its possible link to the RNAi machinery have not been established (Maison et al. 2002).”
- An epigenetic road map for histone lysine methylation (2003, background): “Suv39h Other HMT sase HP1α MMe Me Lysine acetylation Serine phosphorylation Lysine methylation Arginine methylation Methylated DNA shRNAs Transcription factor Heterochromatin protein 1 Polycomb complex”