Nitric oxide and immune response.

By P. Tripathi. Indian Journal of Biochemistry & Biophysics, 2007

1,278 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/ed222ac180969b64ffb5c5f767cf23d629fe992e

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Citations in the corpus

Myeloid derived suppressor cells (2013, background): “ARG1 converts l-arginine into urea and l-ornithine, while iNOS-2 metabolizes it into nitric oxide (NO) and l-citrulline.(16) MDSCs are induced to express these two enzymes at very high levels as a result of exposure to specific cytokines, including the Th2 cytokines TGFβ and IL-10 for ARG1, and the ”
Myeloperoxidase: friend and foe (2005, background): “However, human neutrophils appropriately stimulated have been shown to contain an inducible NO· synthase (iNOS) [282–284], as do tissue macrophages from infected humans [285–288].”
Anti-Inflammatory Effects of Flavonoids: Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT-1 and NF-κB Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF-κB Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated (2007, background): “NO production is increased in inflammation and has proinflammatory and regulatory effects [4, 5].”
A review of the molecular aspects of melatonin’s anti‐inflammatory actions: recent insights and new perspectives (2013, background): “Nitric oxide (NO) is a key molecule influencing various aspects on the inflammatory cascade, ranging from its own production by immunocompetent cells to the recruitment of leukocytes [25].”
Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens (2008, background): “A key antipathogen effector of CAMs is nitric oxide (NO), which is required for host control of intracellular infections, including Mycobacterium species, Toxoplasma gondii , Leishmania species and Trypanosoma cruzi”
Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism (2018, background): “Other kynurenine metabolites, quinolinic, and picolinic acids, can also enhance IFN-γ-dependent iNOS expression (Xu et al., 2017). iNOS is involved in the immune response after gut microbiota exposure and helps to limit inflammation.”
Macrophage defense mechanisms against intracellular bacteria (2015, background): “Using arginine and oxygen, the homodimeric NOS2 generates NO and citrulline, as one subunit transfers electrons between NADPH, FAD, flavin mononucleotide to the heme iron of the second subunit (56, 57).”
Mycobacterium tuberculosis: Success through dormancy (2012, background): “All rights reserved molecules, nitric oxide and superoxide, form the toxic peroxynitrite (Beckman et al., 1990; Bogdan, 2001; Nathan & Ehrt, 2004).”
Regulation of immune responses by L-arginine metabolism (2005, methodology): “This amino acid is used for the biosynthesis of proteins, creatine and agmatine, and it is mainly metabolized by the enzymes ARG and NOS to produce urea and L -ornithine, and nitric oxide (NO) and L -citrulline, respectivel”
Immune modulation by Bacillus subtilis-based direct-fed microbials in commercial broiler chickens◊ (2015, background): “NO has been recognized to play the important roles in the immune response such as pathogenesis, control of infectious diseases, tumors, and autoimmune processes (Bogdan, 2001), therefore dietary B. subtilis might induce iNOS expression following NO production in chicken gut mucosa.”
Tumor‐induced tolerance and immune suppression by myeloid derived suppressor cells (2008, background): “Mouse macrophages, neutrophils, eosinophils, DCs, and NK cells produce NO via NOS2 expression (86), which is triggered mostly by Th1 and inflammatory cytokines such as IFN-a, IL-1, tumor necrosis factor-a (TNF-a), and IFN-g via transcriptional factors nuclear factor (NF)-kB, activator protein-1 (AP-”