Controlling the elongation phase of transcription with P-TEFb.

By B. Peterlin, D. Price. Molecules and Cells, 2006

1,165 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/ec54144fa1c68663ad5dbbbfc03fe3920fd65349

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Citations in the corpus

CpG islands and the regulation of transcription. (2011, positive): “Similarly, gene regulation at the level of transcriptional elongation via RNAPII pausing (controlled by the pause factors DSIF and NELF) and release of RNAPII mediated by P-TEFb (for review, see Peterlin and Price 2006) is reported to be widespread in ES cells (Rahl et al. 2010).”
Defining mechanisms that regulate RNA polymerase II transcription in vivo (2009, positive): “, but others rely on different mechanisms to recruit P-TEFb indirectly (reviewed in ref”
Zelda Binding in the Early Drosophila melanogaster Embryo Marks Regions Subsequently Activated at the Maternal-to-Zygotic Transition (2011, background): “For example, ZLD could recruit factors, such as P-TEFb, that work to release stalled RNA polymerase II [37] or, similar to b-catenin, recruit chromatin-modifying enzymes [25].”
Control of Embryonic Stem Cell State (2011, background): “Control of RNA Polymerase II Transcription factors control at least two major steps in gene expression (Fuda et al., 2009; Peterlin and Price, 2006; Rahl et al., 2010).”
A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers (2010, background): “DRB is an inhibitor of Cdk9, the catalytic subunit of the elongation factor pTEFb [42].”
Pre-mRNA processing reaches back to transcription and ahead to translation. (2009, neutral): “One well-characterized positive factor in higher eukaryotes is the heterodimeric protein PTEFb comprising the Cdk9 kinase and associated cyclin T (also known as CTDK1 in yeast), which generates CTD Ser2P patterns on Pol II elongating into the body of the gene (Peterlin and Price, 2006).”
In vivo dynamics of RNA polymerase II transcription (2007, background): “, an elongation inhibitor that acts on the positive transcription elongation factor P-TEF”
c-Myc regulates transcriptional pause release (2010, background): “Recent studies have shown that an additional level of regulation must occur subsequent to initiation at certain genes and have proposed that certain transcription factors regulate this step (Core and Lis, 2008; Margar-itis and Holstege, 2008; Peterlin and Price, 2006).”
Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers. (2010, background): “Additional regulatory steps can occur subsequent to recruitment of the transcription apparatus, and these are known to play important roles in controlling the expression of a subset of genes (Core and Lis, 2008; Margaritis and Holstege, 2008; Peterlin and Price, 2006).”
Progression through the RNA polymerase II CTD cycle (2009, background): “In mammalian cells, the Cdk9 kinase subunit of the positive elongation factor P-TEFb phosphorylates CTD Ser2 as well as the elongation factor Spt4/Spt5 (also known as DSIF) (reviewed in Peterlin and Price, 2006).”