Cell Therapy of α-Sarcoglycan Null Dystrophic Mice Through Intra-Arterial Delivery of Mesoangioblasts

By M. Sampaolesi, Y. Torrente, A. Innocenzi, R. Tonlorenzi, G. D’Antona, M. Pellegrino, R. Barresi, N. Bresolin, M. Gabriella Cusella De Angelis, K. Campbell and 2 more. Science, 2003

642 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Surgery

View Paper: https://www.semanticscholar.org/paper/eac4c6b2ebb30da1fc6f99415af700da90ef65b0

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Citations in the corpus

Satellite cells and the muscle stem cell niche. (2013, background): “First, it was found that -sarcoglycan / mesoangioblasts can be transduced in vitro with -sarcoglycan expressing lentiviral vector and robustly generate -sarcoglycan myofibers following transplantation into -sarcoglycan / mice (a model for limb girdle muscular dystrophy) via intra-artery injection (4”
Building muscle: molecular regulation of myogenesis. (2012, background): “…mesoangioblasts, pericytes, CD133 (Prom1)+ progenitors, and PW1 (Peg3)+ interstitial cells are able to participate in the formation of multinucleated myotubes (Ferrari et al. 1998; Gussoni et al. 1999; Sampaolesi et al. 2003; Torrente et al. 2004; Dellavalle et al. 2007; Mitchell et al. 2010).”
An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration (2011, background): “Although functional muscle stem cells have been reported to arise from a variety of non-muscle origins (Dellavalle et al., 2007; Gussoni et al., 1999; Mitchell et al., 2010; Sampaolesi et al., 2003; Torrente et al., 2004), our data reveal that such unorthodox muscle stem cell populations must contai”
Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage (2012, positive): “Skeletal muscle regeneration was first properly described in the 1860s, but almost a century elapsed before the cellular mechanisms of this process were resolved (Scharner and Zammit, 2011).”
The Skeletal Muscle Satellite Cell: The Stem Cell That Came in From the Cold (2006, background): “Whether satellite cell numbers declinewith age is controversial and probably varies among different muscles and species (e.g., Schafer et al. 2005; T h e Jo u rn al o f H is to ch em is tr y & C yt o ch em is tr y Shefer et al. 2006).”
Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): The next decade (2013, background): “One of the experimental therapies for muscular dystrophy patients includes transplantation of mesoangioblasts (Minasi et al., 2002; Sampaolesi et al., 2003, 2006).”
Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration (2011, background): “Whereas these cells can be injected into the circulation in myopathic mouse models to reconstitute skeletal muscle (Sampaolesi et al., 2003), it is likely from the results obtained in our model that endogenous mesoangioblasts are not spontaneously mobilised for regenerative myogenesis in the…”
Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. (2005, background): “The surface phenotype of these cells (Tie2+CD13+Sca1+CD31−CD45−) was reminiscent of that of certain types of mesenchymal progenitor cells (MPCs), including mesoangioblasts (Sampaolesi et al., 2003).”
Muscle satellite cells adopt divergent fates (2004, background): “, 2002), and blood vessel–derived mesoangioblasts too have myogenic potential (De Angelis et al., 1999; Cusella De Angelis et al., 2003; Sampaolesi et al., 2003).”
Stem cell plasticity: time for a reappraisal? (2005, positive): “Intra-arterial delivery of genetically-modified mesoangioblasts led to repopulation and massive replacement of sarcoglycan-deficient fibers in a murine model of limb-girdle muscular dystrophy.(69) This study indicates that mesoangioblasts that have been expanded in vitro from an easily accessible so”