Microbiota and SCFA in Lean and Overweight Healthy Subjects

By A. Schwiertz, D. Taras, K. Schäfer, S. Beijer, N. Bos, Christiane Donus, P. Hardt. Obesity, 2010

2,395 citations recorded by the source corpus.

Subfields: Molecular Biology, Physiology, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/e6c2a313901954a33902df6f3ca052f79c17def7

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Citations in the corpus

Meta-analyses of human gut microbes associated with obesity and IBD (2014, background): “Methanobrevibacter smithii + + [22,23]”
Association between body mass index and Firmicutes/Bacteroidetes ratio in an adult Ukrainian population (2017, background): “In some studies, the fecal concentrations of Bacteroides were positively correlated with body mass index (BMI) [25], and predominance of Bacteroidetes in overweight and obese individuals was demonstrated [26].”
Intestinal microbiota in patients with nonalcoholic fatty liver disease (2013, neutral): “ALT (U/L)** 17 (6-41) b 32 (14-54) 69 (22-168)”
The Role of Microbial Amino Acid Metabolism in Host Metabolism (2015, result): “Recent studies have also shown that overweight and obese humans had higher fecal SCFA concentrations than their lean counterparts on a similar diet, confirming that colonic fermentation also differs according to body weight in humans [75,83].”
Human genetics shape the gut microbiome. (2014, neutral): “smithii has been associated with a lean phenotype inmultiple studies (Million et al., 2012, 2013;Schwiertz et al., 2010; Armougom et al., 2009; Le Chatelier et al., 2013), raising the possibility that methanogens are key components of the consortium for regulating host phenotype.”
Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice (2016, background): “Butyricimonas, a butyrate producer (23), and Prevotella, a propionate producer (24), increased the relative abundance more dramatically in the ProPre group than in the other groups.”
Impact of antibiotics on the human microbiome and consequences for host health (2022, background): “Some studies suggest that an increased ratio of Firmicutes to Bacteroidetes rather than specific levels is as- sociated with obesity (Kasai et al., 2015), though results are con- flicting (Duncan et al., 2008; Schwiertz et al., 2010).”
Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans. (2011, background): “There are conflictingdata concerning the linkbetween thegutmicrobiota and adiposity in humans (19, 20, 22, 30, 31), and inmice, forwhich reports have either shown that the absence of a microbiota does protect or does not protect against diet-induced obesity (11, 32).”
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites. (2016, neutral): “, 2013), SCFA concentrations are increased in feces of obese humans compared to lean controls (Schwiertz et al., 2010).”