Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans.

By R. Jumpertz, D. S. Le, Peter J. Turnbaugh, Cathy Trinidad, C. Bogardus, Jeffrey I. Gordon, J. Krakoff. American Journal of Clinical Nutrition, 2011

1,158 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/97dfdd35fcb42d28d03eb2b06973b0dc2a387494

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Citations in the corpus

Meta-analyses of human gut microbes associated with obesity and IBD (2014, background): “Many studies show an increased ratio of Firmicutes:Bacteroidetes [8,13–19] although some other studies show no trend, or even the opposite trend [20–24].”
Microbiota regulate intestinal absorption and metabolism of fatty acids in the zebrafish (2012, background): “Conversely, obese humans (Ley et al., 2006; Turnbaugh et al., 2009), humans consuming a high-calorie diet (Jumpertz et al., 2011), hyperphagic obese ob/ob mice (Ley et al., 2005), mice fed high-calorie Western diets (Turnbaugh et al., 2008; Hildebrandt et al., 2009; Murphy et al., 2010), and…”
The Impact of Diet and Lifestyle on Gut Microbiota and Human Health (2014, background): “In an inpatient study [126], altering dietary energy load in lean and obese adults induced rapid changes in the proportional abundance of Bacteroidetes and Firmicutes.”
The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation (2016, background): “A high-calorie diet shifts the microbial ecology toward Firmicutes at the expense of Bacteroidetes, thus increasing the energy harvesting capacity of the microbiota [57].”
Host remodeling of the gut microbiome and metabolic changes during pregnancy. (2012, methodology): “Stool Energy Content and Metagenomic Analysis Gut microbial community composition has been linked to how efficiently energy can be extracted from components of the diet reaching the colon and undergoing bacterial fermentation (Jumpertz et al., 2011; Turnbaugh et al., 2006, 2009a, 2009b).”
The Firmicutes/Bacteroidetes Ratio: A Relevant Marker of Gut Dysbiosis in Obese Patients? (2020, background): “Indeed, the gut microbiota is involved in energy homeostasis by extracting energy from foodstuffs through fermentation processes and formation of short chain fatty acid (SCFAs) [11,12].”
Human Gut Microbiota Changes Reveal the Progression of Glucose Intolerance (2013, background): “[13] found no difference in the proportions of fecal microbiota between”
The human gut microbiota: Metabolism and perspective in obesity (2018, positive): “A crossover clinical trial observed that a 20% increase in the Firmicutes phylum abundance was associated with an increase of 150 kcal in energy harvest.(81) Finally, one study reported a decrease in the Firmicutes-to-Bacteroidetes ratio after weight loss by obese individuals (Table 1).”
The chicken gastrointestinal microbiome. (2014, background): “In mice and humans, Firmicutes have been shown to have a positive relationship with the ability to harvest energy from the diet (Turnbaugh et al., 2006, 2008; Jumpertz et al., 2011), and the Firmicutes : Bacteroides ratio may also be important for optimum physiology and nutrition (Mariat et al.”
High-fat diet alters gut microbiota physiology in mice (2013, background): “While many studies have shown that microbial diversity is altered by dietary changes (Clavel et al., 2005; Martinez et al., 2009; Jumpertz et al., 2011; Kau et al., 2011), much less is known about the impact of diet on the metabolic potential of gut microbiota (Martin et al., 2010; McNulty et al.,…”
Intestinal permeability – a new target for disease prevention and therapy (2014, background): “In humans, overfeeding alters the bacterial composition of the commensal microbiota in healthy individuals in a way that results in increased energy harvest from food [232].”
The Role of Microbial Amino Acid Metabolism in Host Metabolism (2015, background): “In addition, intestinal bacteria are known to have a major impact on nutrient absorption [6,71,100].”
A Guide to Enterotypes across the Human Body: Meta-Analysis of Microbial Community Structures in Human Microbiome Datasets (2013, background): “In humans, excess energy intake above that needed for weight maintenance has been shown to reduce Bacteroides levels [34].”