Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes.

By L. Monnier, E. Mas, C. Ginet, F. Michel, L. Villon, Jean-Paul Cristol, C. Colette. Journal of the American Medical Association (JAMA), 2006

2,419 citations recorded by the source corpus.

Subfields: Clinical Biochemistry, Endocrinology, Diabetes and Metabolism

View Paper: https://www.semanticscholar.org/paper/e5d8a6b9b13f8926da2d9f07c115d7a50dd4810b

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In Endocrinology, Diabetes and Metabolism

1. P. Zimmet
2. J. Shaw
3. David W. Dunstan
4. P. Calder
5. Antonio Ceriello
6. V. Basevi
7. W. Westcott
8. S. Grundy

Citations in the corpus

• The Role of Oxidative Stress and Antioxidants in Diabetic Wound Healing (2021, background): “With acute glucose fluctuations, the PKC pathway is activated while inflammatory factors and adhesion molecules were secreted [56, 57], which further results in endothelial dysfunction and oxidative stress of the peripheral nerve.”
• Breaking Up Prolonged Sitting Reduces Postprandial Glucose and Insulin Responses (2012, background): “Although larger reductions in postprandial glycemia have yielded clinical benefits to surrogate cardiovascular end points, including carotid intima-media thickness (8), smaller differentials in the postprandial glucose seen in response to pharmaceutical agents, generally comparable in magnitude to t”
• Oscillating Glucose Is More Deleterious to Endothelial Function and Oxidative Stress Than Mean Glucose in Normal and Type 2 Diabetic Patients (2008, background): “Other factors, such as the activation of inflammation, could be involved; however, we are able to confirm that glucose oscillation is accompanied by an increased excretion of free 8-iso PGF2 in the 24 h of each study (34).”
• International Consensus on Use of Continuous Glucose Monitoring (2017, background): “• Benefits of rtCGM use have also been reported in individuals with T2D who are managed with or without intensive insulin treatment (44-46) [B,C,C].”
• Variability of Blood Glucose Concentration and Short-term Mortality in Critically Ill Patients (2006, neutral): “001 Duration of mechanical ventilation, h 26 [12–88] 39 [17–113] 0.”
• Dietary factors and low-grade inflammation in relation to overweight and obesity (2011, positive): “better the mean glucose excursions following an oral glucose load, were associated with urinary excretion of 8-iso PGF2a as a marker of oxidative stress within 2–3 h after the challenge((550)), and oral glucose and/or high fat additively increased inflammatory markers (CRP and IL-6) and oxidative st”
• Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 Crisis (2020, background): “Even a single high glycemic index meal has been associated with an immediate increase of inflammatory cytokines and C-reactive protein [148,149].”