Free radicals in the physiological control of cell function.

By W. Dröge. Physiological Reviews, 2002

9,942 citations recorded by the source corpus.

Subfields: Biochemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/e5cae7c12e3e0c307e87eebd62271c36037b609d

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Citations in the corpus

The effects of oxidative stress on female reproduction: a review (2012, background): “The presence of excessive amounts of ROS can increase Ca levels, thereby promoting its involvement in pathways such as caldmodulin-dependent pathways [49,55].”
Reactive Oxygen Species in Inflammation and Tissue Injury (2014, positive): “At ‘‘physiological concentrations,’’ ROS function as signaling molecules that regulate cell growth, the adhesion of cells toward other cells, differentiation, senescence, and apoptosis (102, 413).”
Mechanisms of Cell Death in Oxidative Stress (2007, neutral): “Using purified enzymes and isolated cells, various pathways for bio-transformation of the lipid aldehyde have been identified, including enzyme-mediated oxidation, reduction, and GSH role for protein modification by 4-HNE in the pathogenesis of several diseases ( e.g., alcohol-induced liver…”
Hemocytes of the carpet shell clam (Ruditapes decussatus) and the Manila clam (Ruditapes philippinarum): Current knowledge and future prospects (2009, background): “Reactive nitrogen species (RNS) production is catalysed by the enzyme NO synthase (NOS) and starts with the production of the NO radical (NO•), which may then be converted to various other RNS such as nitrosonium cation (NO+), nitroxyl anion (NO−) or peroxynitrite (ONOO−) (Dröge, 2002).”
Essential fatty acids: biochemistry, physiology and pathology (2006, background): “Smooth muscle cells are a major source of ROS in the vasculature [151].”
Mitochondrial formation of reactive oxygen species (2003, background): “Whilst small fluctuations in the steady-state concentration of these oxidants may actually play a role in intracellular signalling (Droge, 2002), uncontrolled increases in the steady-state concentrations of these oxidants lead to free radicalmediated chain reactions which indiscriminately target pro”
Life and death: metabolic rate, membrane composition, and life span of animals. (2007, background): “The role of ROS and other related molecules in normal physiological regulatory processes is extensively reviewed elsewhere (82).”
Antioxidant response mechanism of freshwater microalgae species to reactive oxygen species production: a mini review (2020, background): “lar oxygen with ubisemiquinone bound to the Q0 site [48].”
Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury (2011, background): “Most of the oxidants and their byproducts are metabolized by various enzymes and small molecule antioxidants [97].”
Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection (2011, background): “Free radicals are highly active with other molecules, such as DNA and lipids, pairing with their single electrons and causing oxidation of those molecules (15).”