Life's Complexity Pyramid

By Zoltn Oltvai, Albert-László Barabási. Science, 2002

507 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/df31563e3add83abcec9c7ef8a0b73970719f4b8

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Citations in the corpus

Analyzing and modeling real-world phenomena with complex networks: a survey of applications (2007, background): “Processes in living organisms are basically divided and lin ked in three levels of complexity [327]: (i) metabolic and signaling pathways , which are determined by (ii) the network of interacting proteins , whose production is controlled by (iii) the genetic Regulatory network .”
Integrating 'omic' information: a bridge between genomics and systems biology. (2003, background): “In a Y2H protein–protein interaction network, proteins with large numbers of potential interaction partners, or ‘hubs’, tend to be essential [60, 61 ].”
GMD@CSB.DB: the Golm Metabolome Database (2005, background): “The recent mining and exploitation of data by multiparallel 'omics' technologies open up the possibility to gain comprehensive insight into the understanding of biological systems (Kitano, 2002; Oltvai and Barabási, 2002; Fernie et al., 2004).”
Approaches for extracting practical information from gene co-expression networks in plant biology. (2007, background): “The complexity of biological networks has a hierarchy (Oltvai and Barabasi 2002).”
Parallel analysis of transcript and metabolic profiles: a new approach in systems biology (2003, unknown): “…combined studies of the transciptome and a subset of the proteome have been carried out in Saccharomyces cerevisiae (Futcher et al. , 1999; Gygi et al. , 1999; Ideker et al. , 2001a), facilitating the use of systems-biology approaches (Ideker et al. , 2001b; Kitano 2002; Oltvai & Barabasi, 2002).”
Centrality Analysis Methods for Biological Networks and Their Application to Gene Regulatory Networks (2008, background): “The interaction of biological entities such as genes, proteins and metabolites is of great interest in life science research and is increasingly important for systems biological approaches (Oltvai and Barabási (2002); Kitano (2002)).”
Evolutionary conservation of motif constituents in the yeast protein interaction network (2003, background): “Many biological functions are carried out by the integrated activity of highly interacting cellular components, referred to as functional module”