Identification of severe acute respiratory syndrome in Canada.

By S. Poutanen, D. Low, B. Henry, S. Finkelstein, D. Rose, K. Green, Raymond Tellier, R. Draker, D. Adachi, M. Ayers and 10 more. New England Journal of Medicine, 2003

1,161 citations recorded by the source corpus.

Subfields: Epidemiology, Infectious Diseases

View Paper: https://www.semanticscholar.org/paper/deb2930c1392809268290dc20d2f18ddd259dd07

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Citations in the corpus

Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area. (2003, neutral): “Median (IQR) age, y 45 (34-57) Women 88 (61) Comorbid illness Diabetes 16 (11) Cardiac disease 12 (8) Cancer 9 (6) COPD 2 (1) Chronic renal failure† 2 (1) Exposure history‡ Travel 3 (2) Hospital 111 (77) A§ 82 (74) B 8 (7) C 7 (6) Other 14 (13) Home 35 (24)”
Angiotensin-converting enzyme 2 protects from severe acute lung failure (2005, background): “However, mortality following SARS coronavirus infections approaches almost 10% owing to the development of ARDS [14] [15] [16] .”
SARS: Systematic Review of Treatment Effects (2006, background): “Because the urgency of the international outbreak did not allow time for efficacy studies, physicians in Canada and Hong Kong treated the earliest patients with intravenous ribavirin, based on its broad-spectrum antiviral activity [9,10].”
Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study (2003, background): “[1] [2] [3] [4] The clinical, radiological, and other investigative findings at initial presentation have been previously described, [5] [6] [7] but the temporal progression is unclear.”
Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis (2004, background): “The upper respiratory tract symptoms cannot be explained by our findings, but patients with SARS might be susceptible to secondary infections [18].”
Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome (2003, positive): “5 The clinical symptoms of human metapneumovirus infection vary from mild upper-respiratory-tract disease to severe bronchiolitis and pneumonia.”
An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus (2004, neutral): “The virus is highly contagious and the clinical course is severe, with a high mortality rate [18] [19] [20] .”
The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex (2003, background): “coronavirus associated with severe acute respiratory syndrome (HCoV-SARS) (17, 34, 52, 53 ).”
A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice (2004, background): “Public health measures have successfully identified and contained outbreaks of the severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) [1] [2] [3] [4] [5] , but concerns remain over the possibility of future recurrences.”
SARS‐coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS (2009, background): “In Toronto, the SARS outbreak was associated with loss of lives, considerable burden on the healthcare system and a huge economic impact [13] [14] [15] .”
Coronavirus Pathogenesis (2011, background): “SARS is a novel infectious disorder that was first diagnosed in China in November 2002 and subsequently spread worldwide (Booth et al., 2003; Dwosh et al., 2003; Holmes, 2003; Ksiazek et al., 2003; Lee et al., 2003; Peiris et al., 2003b; Poutanen et al., 2003; Tsang et al., 2003; Varia et al., 2003;”
When individual behaviour matters: homogeneous and network models in epidemiology (2007, background): “There were no secondary cases reported from the individual from Vancouver; in contrast, the infected individual from Toronto went on to infect five other people, which led to an outbreak of 200 cases in Toronto (Poutanen et al. 2003).”
Systematic Comparison of Two Animal-to-Human Transmitted Human Coronaviruses: SARS-CoV-2 and SARS-CoV (2020, background): “The following month, there were clusters of atypical pneumonia reported in other parts of mainland China, Hong Kong [21], Canada [22], and Singapore [23].”