Viruses and apoptosis

By B. Thomson. International journal of experimental pathology (Print), 2001

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Antiviral Actions of Interferons (2001, background): “The E6 protein of HPV and SV40 large-T antigen also impair p53-mediated apoptosis (159, 375, 405).”
Cytotoxic T lymphocytes: all roads lead to death (2002, background): “To further support replication in the host, viruses encode inhibitors that interfere with specific components of the apoptotic respons”
Apoptosis in development (2000, background): “Disorders associated with insufficient cell death include autoimmunity and cancer, but it has also become clear that many, if not all, viruses possess mechanisms to forestall apoptosis and provide a living host to nurture virus propagatio”
The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet (2002, background): “Both proteins may ensure nuclear degradation when caspase activation is limited or compromised, as may be the case during viral infection.(127,128) or they may be responsible for the caspaseindependent DNA degradation that has been observed in plants, fungi and protozoa.”