The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet
By G. van Loo, X. Saelens, Maria van Gurp, M. MacFarlane, S. Martin, Peter Vandenabeele. Cell Death and Differentiation, 2002
674 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/b3c76663b86dc88270757ab309780fd443d8a7f9
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Citations in the corpus
- Bcl-2-family proteins and the role of mitochondria in apoptosis. (2003, background): “Introduction Mitochondria play an important role in apoptotic cell death by releasing key effector proteins [1], including cytochrome c and Smac/DIABLO, from the mitochondrial intermembrane space (IMS).”
- Magnetic Nanomaterials for Hyperthermia-based Therapy and Controlled Drug Delivery (2011, background): “[1] The approach involves raising the temperature of local environment of a tumor resulting in changing the physiology of diseased cells finally leading to apoptosis.[2] This treatment modality complements currently available treatments including”
- Apoptosis: A Review of Programmed Cell Death (2007, background): “The first group consists of cytochrome c, Smac/DIABLO, and the serine protease HtrA2/Omi (Cai et al., 1998; Du et al., 2000; Loo et al., 2002; Garrido et al., 2005).”
- Role of hypoxia in cancer therapy by regulating the tumor microenvironment (2019, background): “The Bcl-2 family can be divided into two categories: anti-apoptotic proteins such as Bcl-2, Bcl-xl, Myeloid cell leukemia-1 (Mcl-1), and cell death abnormality gene 9 (CED9); and pro-apoptotic proteins including mainly BCL2-associated X protein (Bax), BCL2 antagonist/killer (Bak), Bcl-xs, Bad, and B”
- The Role of Resveratrol in Cancer Therapy (2017, background): “The intrinsic pathway is triggered by the dispensation of apoptogenic factors such as Omi/HtrA2, Smac/DIABLO, cytochrome c, apoptosis-inducing factors (AIFs), endonuclease G, caspase-2, or caspase-9 from the mitochondrial intermembrane space [100].”
- The role of the mitochondrion in plant responses to biotic stress (2007, positive): “In part, this hypothesis derives from studies of animal apoptosis, where mitochondria play an active role (see reviews by Bratton and Cohen 2001, Crompton 1999, Kuwana and Newmeyer 2003, Ly et al. 2003, Newmeyer and Ferguson-Miller 2003, van Loo et al. 2002).”