Apoptosis in development

By P. Meier, A. Finch, G. Evan. Nature, 2000

1,076 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/9eafaa522e5d9afe4ad365dabc58e94e15b05568

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In Molecular Biology

Citations in the corpus

Axon pruning: an essential step underlying the developmental plasticity of neuronal connections (2006, background): “…elimination have become synonymous with phenomena that are associated with this regressive phase of nervous system development (Purves & Lichtman 1980; Cowan et al. 1984; Burek & Oppenheim 1996; Lichtman & Colman 2000; Meier et al. 2000; Raff et al. 2002; Yuan et al. 2003; Luo & O'Leary 2005).”
Overview of cell death signaling pathways (2005, background): “Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.”
Validating survivin as a cancer therapeutic target (2003, background): “Repression of CDK1 and other genes with CDE and CHR promoter elements during DNA damage-induced G(2)/M arrest in human cells.”
Cell Death in Pseudomonas aeruginosa Biofilm Development (2003, background): “In multicellular organisms, cell death is a normal component of development (18, 43).”
Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals (2010, background): “Homeostasis is carried out in a genetically programmed manner by a process referred to as apoptosis (programmed cell death) [53-55].”
Heat Shock-Induced Apoptosis in Preimplantation Bovine Embryos Is a Developmentally Regulated Phenomenon (2002, background): “Apoptosis plays a role in mammalian development as a quality control mechanism to eliminate cells that are damaged, nonfunctional, abnormal, or misplaced [14–16].”
Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis. (2008, background): “Furthermore, apoptosis was found to be an evolutionarily conserved means of tissue remodeling during normal development (115).”
On the origin, evolution, and nature of programmed cell death: a timeline of four billion years (2002, background): “The evolutionary conservation of programmed cell death in the animal kingdom does not only involve its existence and role, but extends to some central aspects of its genetic control, and to important aspects of its most frequent phenotype, apoptosis.(5,16,18,20,24,25,63,64) In all cases that have be”
β-Cell death during progression to diabetes (2001, background): “First, at various times during development, certain tissues undergo a remodelling process involving apoptosi”