The role of chromatin during transcription.

By Bing Li, M. Carey, Jerry L. Workman. Cell, 2007

3,663 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/dcf44deff958f5b84673b4a817a31dad808d9d0d

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In Molecular Biology

Citations in the corpus

Recombination centres and the orchestration of V(D)J recombination (2011, background): “Many factors (such as HATs, histone methylases, chromatin remodelling complexes and histone chaperones) associate and move with RNA polymerase II through the transcription unit, leading to further nucleosome remodelling and additional activating histone modification”
γ-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin (2008, background): “The organization of DNA into chromatin is not only important for resolving problems of spatial accommodation and organization, but it is also essential for the functional utilization of the DNA and the proper coordination of its metabolic activities (7,8).”
The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3. (2007, background): “Conformation of chromatin is one of the key regulators of transcription; untranscribed genes are compacted in heterochromatin, whereas transcribed genes are in euchromatin, wherein transcriptional complexes are accessible to the target DNA ( 4 ).”
Control of Embryonic Stem Cell State (2011, background): “They can also recruit various chromatin regulators to promoter regions to modify and mobilize nucleosomes in order to increase access to local DNA sequences (Li et al., 2007).”
Nucleosome positioning and gene regulation: advances through genomics (2009, neutral): “and histone tail modifications (methylation and acetylation”
Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA non-homologous end-joining (2010, positive): “Thus, as for transcription, HDACs and HATs might function in a coordinated manner in the DDR to promote both open and repressed chromatin states to facilitate distinct event”
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression. (2013, background): “Histone proteins are modified post-translationally, and these modifications include acetylation, methylation, ubiquitylation, and phosphorylation (Strahl and Allis 2000; Zhang and Reinberg 2001; Li et al. 2007).”
Charting histone modifications and the functional organization of mammalian genomes (2011, background): “In particular, chromatin is heavily influenced by transcription factor networks and transcriptional processes, which extensively harness chromatin modifiers and nucleosome remodeller”
Pre-mRNA processing reaches back to transcription and ahead to translation. (2009, neutral): “As mentioned above, this complex is recruited to elongating Pol II in part through direct interaction of its components, especially Pcf11 CID with the CTD Ser2P elongation mark (Bentley, 2005; Licatalosi et al., 2002; Proudfoot, 2004).”
HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention (2007, background): “…of us have excitingly witnessed, the field has experienced an exponential growth in the past decade and is gradually reaching its maturity (Figure 2) (reviewed by Jenuwein and Allis, 2001; Lin and Dent, 2006; Goldberg et al., 2007; Kouzarides, 2007; Li et al., 2007; Shahbazian and Grunstein, 2007).”
Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains. (2008, background): “…could have underestimated the number of potential barriers bound by CTCF. CTCF demarcates active and repressive regions of the genome The acetylation of several histone residues is known to mark the active regions of the genome (Roh et al. 2005, 2006; Berger 2007; Li et al. 2007; Wang et al. 2008).”