ARGONAUTE4 Control of Locus-Specific siRNA Accumulation and DNA and Histone Methylation

By Daniel Zilberman, Xiaofeng Cao, Steven E. Jacobsen. Science, 2003

1,098 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/dbd73a8a2e45d67e52ffbf913a2bb4dd6d68bc7d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Plant Science

Citations in the corpus

Perspective: machines for RNAi. (2005, background): “Both siRNAs and miRNAs can also trigger methylation of the DNA of protein-coding genes that share their sequence in plants (Zilberman et al. 2003; Bao et al. 2004) and perhaps even in mammals (Kawasaki and Taira 2004; Morris et al. 2004). siRNAs can direct the construction of repressive…”
A pathway for the biogenesis of trans-acting siRNAs in Arabidopsis. (2005, background): “2164 GENES & DEVELOPMENT 19:2164–2175 © 2005 by Cold Spring Harbor Laboratory Press ISSN 0890-9369/05; www.genesdev.org et al. 2005; Onodera et al. 2005; Yu et al. 2005), and require the RNA-dependent RNA polymerase (RdRp) RDR2, the Dicer-like protein DCL3 (Xie et al. 2004), the Argonaute protein AG”
Specificity of ARGONAUTE7-miR390 interaction and dual functionality in TAS3 trans-acting siRNA formation. (2008, background): “The phenotype of AGO4 mutants does not overlap the phenotype of TAS3 tasiRNA-deficient mutants (Zilberman et al., 2003).”
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. (2004, background): “, 2002; gene silencing mechanisms (Bohmert et al., 1998; Fagard et al., 2000; Kidner and Martienssen, 2004; Sasaki et al., 2003; Zilberman et al., 2003) have evolved into multi-protein families.”
The microRNAs of Caenorhabditis elegans. (2003, background): “Similar pathways have been proposed for gene silencing in plants and fungi, with siRNAs targeting mRNA for cleavage during posttranscriptional gene silencing and heterochromatic siRNAs targeting chromatin for histone methylation, triggering heterochromatin formation and consequent transcriptional ge”
Small RNAs in transcriptional gene silencing and genome defence (2009, background): “thaliana indicated that RNA-directed DNA methylation of the FWA transgene requires Dicer (DCL3) and Argonaute (AGO4), and is linked to histone H3 lysine 9 (H3K9) methylation, indicating that RNA-directed DNA methylation and RNAi have common molecular mediator”
Small RNAs and Their Roles in Plant Development (2009, background): “Loss-of-function mutations in AGO4 result in loss of DNA methylation, histone H3K9 methylation, and derepression of heterochromatic loci (Xie et al. 2004, Zilberman et al. 2003).”
microRNA-directed phasing during trans-acting siRNA biogenesis in plants. (2005, background): “For example, DCL3 and RDR2 cooperate in the heterochromatin-associated RNAi pathway, resulting in 24-nucleotide siRNAs from various retroelements and transposons, ribosomal arrays, endogenous direct and inverted repeats, and transgenes containing direct repeats (Chan et al., 2004; Xie et al., 2004; ”
Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. (2005, background): “2004) and have been linked to Ago4, an argonaute protein, histone H3 Lys 9 (H3K9) methylation, and CpXpG DNA methylation (Lindroth et al. 2001; Jackson et al. 2002; Zilberman et al. 2003).”