Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles.

By J. Hillyer, R. Albrecht. Journal of Pharmacy and Science, 2001

703 citations recorded by the source corpus.

Subfields: Biomaterials, Endocrinology, Pharmaceutical Science

View Paper: https://www.semanticscholar.org/paper/dbd0122734fa5b8006e657d4a6fe79467d281929

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Citations in the corpus

Particle size-dependent organ distribution of gold nanoparticles after intravenous administration. (2008, background): “Our results are in agreement with results reported previously by Hillyer and Albrecht [18] who found the highest levels of gold in liver and spleen and lower levels in brain, lung, heart, kidney, small intestine and stomach.”
Titanium dioxide nanoparticles: a review of current toxicological data (2013, background): “In the field of nanomedicine, the GIT uptake of NPs has been the subject of recent efforts to develop effective carriers that enhance the oral uptake of drugs and vaccines [57].”
Optical properties and biomedical applications of plasmonic nanoparticles (2010, background): “For 13 nm CG NPs, the highest amount of gold was detected in liver and spleen after intraperitoneal administration [264].”
Intranasal delivery of biologics to the central nervous system. (2012, background): “In the intestine, colloidal gold nanoparticles have been shown to cross the epithelium and distribute to other tissues through large transepithelial spaces created by degrading enterocytes in a process known as persorption [53].”
Review of health safety aspects of nanotechnologies in food production. (2009, background): “(Jani et al., 1990; Hillery et al., 1994; Hillyer and Albrecht, 2001; Hoet et al., 2004; De Jong et al., 2008).”
Fate and Bioavailability of Engineered Nanoparticles in Soils: A Review (2014, background): “Persorption of ENMs may occur via breaks at the top of the intestine vili (Volkheimer et al., 1968), via tight junction channels between enterocyte cells (Carr et al., 2012) or through gaps created by extruding enterocytes (Hillyer and Albrecht, 2001).”
Acute toxicological effects of copper nanoparticles in vivo. (2006, background): “Nanosized particles can cross small intestine by persorption and further distribute into blood, brain, lung, heart, kidney, spleen, liver, intestine and stomach (Hillyer and Albrecht, 2001).”
Toxicity and cellular uptake of gold nanoparticles: what we have learned so far? (2010, positive): “For example, Hillyer and Albrecht (2001) showed that the absorption of gold nanoparticles following oral administration to mice is size-dependent.”