Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes

By D. Jin, K. Shido, H. Kopp, I. Petit, S. Shmelkov, L. Young, A. Hooper, H. Amano, S. Avecilla, B. Heissig and 12 more. Nature Medicine, 2006

685 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/da57bb18f3ef45f683a46d70fc4c7896da718a84

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. J. Joyce
2. J. Pollard
3. C. Lewis
4. D. Lyden
5. B. Psaila
6. H. Moses
7. Li Yang
8. D. Hanahan

In Molecular Biology

1. J. Joyce
2. D. Hanahan
3. J. Pollard
4. C. Lewis
5. R. Weinberg
6. N. Prabhakar
7. D. Lyden
8. Shahin Rafii

In Oncology

1. J. Joyce
2. J. Pollard
3. R. Weinberg
4. C. Lewis
5. D. Hanahan
6. L. Matrisian
7. A. Richmond
8. B. Psaila

Citations in the corpus

• The metastatic niche: adapting the foreign soil (2009, background): “For example, recruitment of VEGFR1 + haematopoietic progenitor cells (which also express C-X-C chemokine receptor 4 ( CXCR4 )) to sites of neovascularization in ischaemic tissues and growing tumours is dependent on SDF1 released from platelet granule”
• Contribution of platelets to tumour metastasis (2011, background): “Furthermore, systemic deployment of C-X-C motif ligand 12 (CXCL12; also known as SDF1) from platelets regulates neoangiogenesis through the recruitment of haematopoietic progenitor”
• The SDF-1-CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesis. (2007, background): “Capoccia BJ, et al. G-CSF and AMD3100 mobilize monocytes into the blood that stimulate angiogenesis in vivo through a paracrine mechanism.”
• Microenvironmental regulation of metastasis (2009, background): “Platelets are also a potent source of SDF1 that may affect the migration of CXCR4-expressing tumour cells and the recruitment of BMDCs to sites of metastasi”
• The role of myeloid cells in the promotion of tumour angiogenesis (2008, background): “These cells also express TIE2 and various progenitor markers such as SCA1 (also known as LY6A ) and CD117 (also known as KIT”
• Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. (2008, result): “SDF-1/CXCR4 has been implicated in the recruitment of hematopoietic stem and progenitor cells (Balkwill and Coussens, 2004; Jin et al., 2006; Mohle et al., 1998; Peled et al., 1999; Urbich and Dimmeler, 2004), supporting our observation that Gr-1+CD11b+ cells are hematopoietic progenitors.”
• Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): The next decade (2013, background): “Meanwhile, it is clear that the proteolytic activity of MMP-9 is essential for progenitor cell recruitment from the bone marrow, an important issue applied in stem cell mobilization for transplantation and for regenerative medicine (Heissig et al., 2002; Jin et al., 2006).”
• ADAPTIVE AND MALADAPTIVE CARDIORESPIRATORY RESPONSES TO CONTINUOUS AND INTERMITTENT HYPOXIA MEDIATED BY HYPOXIA-INDUCIBLE FACTORS 1 AND 2 (2012, background): “Many angiogenic factors, including PLGF, SDF1, and VEGF, also function as cytokines that recruit proangiogenic cells from distant sites such as the bone marrow (105, 146, 200).”