The metastatic niche: adapting the foreign soil

By B. Psaila, D. Lyden. Nature Reviews. Cancer, 2009

1,279 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/2cc632a2c33dada893a1050776cd747ded8b1780

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Citations in the corpus

Cancer as a metabolic disease (2010, background): “The macrophage fusion hypothesis would also fit with the roles of hematopoietic stem cells in the metastatic niche [208,213].”
EMERGING BIOLOGICAL PRINCIPLES OF METASTASIS (2017, positive): “This niche formation may involve the actions of VEGFR+ bone marrow progenitors (Kaplan et al., 2005), myeloid-derived suppressor cells (MDSCs) (Psaila and Lyden, 2009), or neutrophils (Wculek and Malanchi, 2015).”
Interactions between cancer stem cells and their niche govern metastatic colonization (2011, background): “Stem cells are suspected to rely on signals from their stromal environment, such as localized growth factors that can affect stem cell maintenance and proliferatio”
The basics of epithelial–mesenchymal transition (EMT): A study from a structure, dynamics, and functional perspective (2019, background): “The malignant cells frequently commu- nicates with cells of the microenvironment at primary and metastatic sites as well (Fidler, Kim, & Langley, 2007; Psaila & Lyden, 2009).”
Accessories to the crime: functions of cells recruited to the tumor microenvironment. (2012, positive): “…into specialized vascular niches in primary tumors (Calabrese et al., 2007) as well as metastatic sites (Kaplan et al., 2005; Lyden et al., 2001; Psaila and Lyden, 2009), and (2) the myofibroblastic/MSC subtype of CAFs, likely also present in metastatic vascular stem cell niches (Kidd et al.,…”
Role of Extracellular Matrix in Development and Cancer Progression (2018, background): “Despite doubt over the course of the twentieth century, Paget’s hypothesis was strengthened in the 1970s when Isaiah Fidler’s research demonstrated that successful tumour migration could only occur at certain organ sites [215].”
Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs (2011, background): “Specialized microenvironments called metastatic niches are thought to nurse the outgrowth of metastatic nodules from metastasis-initiating cell”
Microenvironmental regulation of metastasis (2009, background): “These niches, covered in detail in an Opinion piece in this Focus issu”
New horizons in tumor microenvironment biology: challenges and opportunities (2015, background): “Either at primary sites or in vasculature vessels, cancer cells can release microvesicles or soluble factors to adapt incipient metastatic sites into ‘pre-metastatic niches’; for example, systemic factors attract bone marrow-derived macrophages and hematopoietic progenitor cells that are accompanied”
The Cancer Stem Cell Niche: How Essential is the Niche in Regulating Stemness of Tumor Cells? (2015, positive): “The metastatic niches are populated by Gr1+ CD11b+ myeloid cells recruited by LOX and S100A proteins (Erler et al., 2009; Psaila and Lyden, 2009; Yan et al., 2010).”