Mitochondrial metabolism of reactive oxygen species

By A. Andreyev, A. Andreyev, Y. Kushnareva, A. Starkov. Biochemistry (Moscow), 2005

1,455 citations recorded by the source corpus.

Subfields: Biophysics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/da2736242f02634587836b273dbf78e0a3267ef5

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Citations in the corpus

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases (2006, positive): “Mitochondrial insults, including oxidative damage itself, can cause an imbalance between ROS production and removal, resulting in net ROS productio”
The changing faces of glutathione, a cellular protagonist. (2003, background): “Although ROS can be generated at several sites of the ETC (Figure 2; Brand, 2010; Quinlan et al., 2013), complex I and complex III (Venditti et al., 2013) have been shown to be the most important sources of mitochondrial superoxide generation, although significant production of ROS in complex II…”
Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response. (2006, background): “Mitochondria are the major source of ROS within the cell [69,70].”
Reactive Oxygen Species, Oxidative Damage, and Antioxidative Defense Mechanism in Plants under Stressful Conditions (2012, positive): “Some of them produce ROS directly, for example aconitase, whereas some others like 1-galactonoγ lactone dehydrogenase (GAL), are able to feed electrons to ETC [60, 61].”
Reperfusion injury and reactive oxygen species: The evolution of a concept (2015, background): “non-phosphorylating conditions) both of which favor reduction of electron carriers [282,305,307,308].”
Mitochondria, oxidative stress and cell death (2007, background): “sites and enzymes were recently analyzed in detail in a comprehensive review [3].”
Mitochondrial dysfunction and oxidative stress in metabolic disorders - A Step towards mitochondria based therapeutic strategies (2016, neutral): “chemical gradient that generated ATP [42].”
Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. (2014, background): “Good reviews on the current mechanisms of ROS production in mitochondria are available elsewhere for the reader interested in a general background and for those interested in substantially detailed mechanistic depth (3, 13, 201, 202, 308, 397, 416).”
Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa. (2008, background): “Usually, this activity is balanced by antioxidant factors within the intermembrane space and mitochondrial matrix (14).”
Necrotic death as a cell fate. (2006, background): “They are generated primarily in the electron-rich environment of the mitochondrial inner membrane, or through endogenous enzymes such as flavoenzymes, xanthine oxidase, NADPH-oxidase, glucose oxidase, nitric oxide synthase, or transition metals (Andreyev et al. 2005).”
Role of ROS and RNS Sources in Physiological and Pathological Conditions (2016, background): “Experiments with isolated enzymes or mitochondria have shown ROS production by several oxidoreductases located in mitochondrialmembranes [40], whose contribution tomitochondrial ROS production is, however, unknown.”