Innate and acquired immunity in atherogenesis

By C. Binder, Mi-Kyung Chang, P. Shaw, Yury I. Miller, K. Hartvigsen, A. Dewan, J. Witztum. Nature Medicine, 2002

706 citations recorded by the source corpus.

Subfields: Epidemiology, Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/da16445ef4583d215d69c20f8dd071a8a73c0025

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. A. Chawla
2. K. Moore
3. P. Murray
4. J. Odegaard
5. Shizuo Akira
6. A. Tedgui
7. Lata Mukundan
8. Z. Mallat

In Immunology

1. Shizuo Akira
2. P. Murray
3. A. Chawla
4. K. Moore
5. D. Golenbock
6. J. Odegaard
7. G. van Loo
8. A. Tedgui

In Molecular Biology

1. A. Chawla
2. G. van Loo
3. P. Murray
4. K. Moore
5. A. Tedgui
6. Josef M. Penninger
7. Z. Mallat
8. A. Luster

Citations in the corpus

• Antiinflammatory Properties of HDL (2004, background): “Thus, antibodies to the oxidized phospholipids found in MM-LDL appear to be “preloaded” in the innate immune system [29].”
• Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways (2004, background): “The search for proinflammatory signaling cascades activated by endogenous lipoproteins has recently focused on the TLRs, a group of pattern-recognition receptors that activate host defenses in response to microbial-derived ligand”
• Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases. (2018, background): “The recruitment of LDL cholesterol into the arterial wall also leads to activation of the NLRP3 inflammasome, since excess cholesterol is partially deposited as cholesterol crystals [157-158], which are fully internalized by human macrophages by phagocytosis and promote IL-1β and IL-18 generation [1”
• Cytokines in atherosclerosis: pathogenic and regulatory pathways. (2006, background): “Several excellent reviews have been published on the theme of atherosclerosis and inflammation since the founding Ross review (52, 235, 265, 395, 417, 578).”
• Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury (2008, background): “including OxPLs, have been implicated as pathogen-associated molecular patterns that are detected by several conserved pattern-recognition receptors (Binder et al., 2002; Miller et al., 2003b).”
• NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases (2015, neutral): “…. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 302 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 304”
• Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation. (2006, background): “Development and progression of atherosclerotic plaques is dictated by a balance between proand anti-inflammatory factors (Binder et al., 2002;Hansson, 2005).”
• Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL (2003, background): “Moreover, growing evidence suggests that both adaptive and innate immune mechanisms can modulate the progression of atherosclerosi”