Leaving the neighborhood: molecular mechanisms involved during epithelial‐mesenchymal transition

By P. Savagner. Bioessays, 2001

716 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/d829d056e1f47c230ef6429fedde08c594f49f89

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Citations in the corpus

The cadherin-catenin adhesion system in signaling and cancer. (2002, background): “Cross-talk between AJs and growth factor receptors Growth factors such as EGF, HGF/scatter factor (SF), and FGF can induce the dismantling of AJs and can cause a dramatic change in cell morphology and gene expression in which cells shift from an epithelial to a fibroblastic phenotype and initiate a ”
Complex networks orchestrate epithelial–mesenchymal transitions (2006, background): “The triggers and the signalling pathways that regulate EMT have been previously reviewe”
Building epithelial architecture: insights from three-dimensional culture models (2002, background): “To list just a few examples, cells undergo EMT during gastrulation, neural-crest-cell migration and malignant progression of certain epithelial tumour”
Migrating cancer stem cells — an integrated concept of malignant tumour progression (2005, background): “In these tumours, a loss of differentiation, similar to an EMT, is often detectable at the tumour–host interface and is thought to enable cellular detachment, dissemination and finally metastasi”
Epithelial-mesenchymal transition and its implications for fibrosis. (2003, background): “As a result of ligandinducible receptor kinase activation (14), there is a downstream engagement of GTPases from the Ras superfamily (70, 71) or commitment of SH2-SH3 protein domains of the nonreceptor tyrosine kinase (c-Src and Btk) pathways (14, 72) that shift the intracellular balance of small GT”
Cadherin switching (2008, background): “Likewise, when epithelial cells change their relative positions within a tissue, they become motile cells, their cell-cell junctions are disrupted and the actin cytoskeleton is reorganized (Boyer et al., 2000; Gumbiner, 2005; Keller, 2002; Savagner, 2001).”
Long non-coding RNAs with enhancer-like function in human (2010, background): “The Snail family of transcription factors are implicated in the differentiation of epithelia cells into mesenchymal cells (epithelial-mesenchymal transition) during embry- 50 Cell 143, 46–58, October 1, 2010 ª2010 Elsevier Inc. onic development (Barrallo-Gimeno and Nieto, 2005; Savagner, 2001).”