The cadherin-catenin adhesion system in signaling and cancer.

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Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic. (2009, background): “This creates a communication path between cell contact, regulation of cytoskeleton and cell shape, necessary for keeping the epithelial cells immobile and physically linked [10,12–14].”
Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis. (2006, background): “Loss of E-cadherin has been extensively implicated in the progression and dissemination of human cancer (Berx and van Roy, 2001; Conacci-Sorrell et al., 2002; Cavallaro and Christofori, 2004).”
Adherens and tight junctions: structure, function and connections to the actin cytoskeleton. (2008, background): “Loss of p120-catenin-induced stabilization of E-cadherin is linked to tumor progression and invasion [19,20].”
Links between signal transduction, transcription and adhesion in epithelial bud development (2003, background): “A correlation between reduced E-cadherin and elevated nuclear β-catenin has also been observed in vitro and in human cancer”