Faculty Opinions recommendation of Natural RNA circles function as efficient microRNA sponges.

By L. DesGroseillers. 2013

4,668 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/d1bc0c45948546065f90c000154dd072f3a8642b

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In Cancer Research

Citations in the corpus

Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer’s disease (2020, background): “As decreased circCDR1-AS levels lead to downregulation of mRNAs targeted by miR-7 [621], and elevated miRNA-7 levels can downregulate the expression of genes involved in Aβ clearance [622], circCDR1-AS may affect Aβ metabolism.”
Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance. (2014, background): “, 2013), and a circular RNA regulating miR-7 activity in the central nervous system (Hansen et al., 2013; Memczak et al., 2013).”
The bioinformatics toolbox for circRNA discovery and analysis (2020, background): “2013, circRNA was shown to act as a miRNA sponge with examples such as CDR1as [9] and Sry [172].”
Circular RNA (circRNA) in Alzheimer's disease (AD) (2013, neutral): “GENERAL COMMENTARY published: 31 December 2013 doi: 10.3389/fgene.2013.00307”
Circular intronic long noncoding RNAs. (2013, background): “…RNAs with noncanonical 30 ends (Sunwoo et al., 2009; Wilusz et al., 2008; Yin et al., 2012) and circular RNAs produced from backspliced exons (Hansen et al., 2013; Jeck et al., 2013; Memczak et al., 2013) account for many RNAs that lack a poly(A) tail, we report here that ciRNAs represent…”
Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function (2017, background): “It is highly conserved across mammals and not detectable as a linear transcript (3, 9, 10).”
CircRNA: functions and properties of a novel potential biomarker for cancer (2017, background): “Studies have proven that the circular RNAs CDR1as or ciRS-7 [11, 12], circ-SRY [12], circ-ITCH [8], circ- HIPK3 [13], hsa_circ_0000615 [14], and mm9_circ_012559 [15] are able to act as miRNA sponges.”
Complementary sequence-mediated exon circularization. (2014, background): “134 Cell 159, 134–147, September 25, 2014 ª2014 Elsevier Inc. Recently, circular RNAs from human INK4a/ARF (Burd et al., 2010) and CDR1 (Hansen et al., 2013; Hansen et al., 2011) loci were identified and suggested to affect human atherosclerosis risk or regulate mRNA expression, thus shedding new…”