Complementary sequence-mediated exon circularization.

By Xiao-Ou Zhang, Hai-Bin Wang, Yang Zhang, Xuhua Lu, Ling-Ling Chen, Li Yang. Cell, 2014

1,756 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/7eae84e9159f98424f1db6232965d752b5290c84

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Citations in the corpus

Induction of tumor apoptosis through a circular RNA enhancing Foxo3 activity (2016, background): “predominantly found in the cytoplasm and contain exons, known as circRNAs.(5) A relatively smaller group of circular”
Past, present, and future of circRNAs (2019, positive): “Evolutionary conservation of circRNAs circRNAs are present in most organisms, including Archaea, plants, yeast, and most metazoans (Danan et al , 2012; Wang et al , 2014; Broadbent et al , 2015; Lu et al , 2015; Sun et al , 2016; Ji et al , 2019).”
The bioinformatics toolbox for circRNA discovery and analysis (2020, background): “Notably, one gene can generate different circRNAs, which can be affected by the competition of RNA pairing across the flanking introns [24, 25].”
Comparison of circular RNA prediction tools (2015, methodology): “…of two non-treated RNA samples derived from Hs68 fibroblast (SRR444655 and SRR444975) and two RNase R treated samples (SRR444974 and SRR445016), we compared five different circRNA predicting algorithms: find circ (7), MapSplice (17), CIRCexplorer (10), cir-cRNA finder (11), and CIRI (12).”
Circular RNAs: diversity of form and function (2014, methodology): “Genome-wide RNA-sequencing analysis has now suggested there are a staggering number of circles produced by backsplicing (Table 2; Salzman et al. 2012, 2013; Jeck et al. 2013; Memczak et al. 2013; Ashwal-Fluss et al. www.rnajournal.org 1833 2014; Guo et al. 2014; Zhang et al. 2014).”
Circular RNA and its mechanisms in disease: From the bench to the clinic. (2018, background): “With regard to intron pairing, alternative formation of inverted repeated Alu elements in flanking introns and competition between RNA pairings across flanking introns or within individual introns can lead to alternative circularization, resulting in the production of multiple circRNAs and linear tr”
Detecting circular RNAs: bioinformatic and experimental challenges (2016, methodology): “…rate due to the biochemical variability of RNase R. qPCR validation has shown that some experimentally validated circRNAs are depleted by RNase R, including human CDR1as , a CAMSAP1 isoform with intron retention, MAN1A2 , NCX1 and Drosophila melanogaster Pangolin and Ank2 (REFS 3,4,7,26,57) .”
Circular RNA: A new star of noncoding RNAs. (2015, background): “first proposed a model of alternative circularization that is similar to alternative splicing [18] (Fig.”