Rapid and selective induction of BDNF expression in the hippocampus during contextual learning

By Jeremy Hall, K. Thomas, Barry J. Everitt. Nature Neuroscience, 2000

658 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/d1b7ef9c88112eb770f0be47ad46b41f9031b6a8

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Citations in the corpus

The Influence of Exercise on Cognitive Abilities (2013, neutral): “learning tasks (80,104) to demonstrations that genetic deletion”
Transcription Factors in Long-Term Memory and Synaptic Plasticity (2009, positive): “Zif 268 is rapidly regulated after associative learning such as song learning in birds, fear-conditioning and spatial learning in rats, and visual-paired association in monkeys (33, 59, 81, 84, 85, 105, 147, 158, 159, 185, 209, 238, 239).”
EPIGENETIC REGULATION OF BDNF GENE TRANSCRIPTION IN THE CONSOLIDATION OF FEAR MEMORY (2008, background): “Similarly, there is increasing behavioral evidence indicating that bdnf gene expression is induced in the hippocampus after contextual and spatial learning and that this mechanism is essential for normal learning and memory (Linnarsson et al., 1997; Hall et al., 2000).”
Brain-derived neurotrophic factor. (2004, background): “Rapid and selective induction of BDNF expression in the hippocampus during contextual learning has been demonstrated (Hall et al., 2000), and function-blocking antibodies to BDNF (Alonso et al., 2002), BDNF knockout (Linnarsson et al., 1997), knockout of forebrain trkB signalling (Minichiello et…”
A computational theory of hippocampal function, and empirical tests of the theory. (2006, background): “Using the same paradigm Hall et al. (2000) have demonstrated a relationship between contextual fear memory and the expression of LTP-related immediate early genes (i.”
Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories (2007, methodology): “For the probe phase of the MWM, both groups showed statistically similar latencies to the target quadrant; however, GFP mice displayed a greater number of target platform crossings than CRE mice (Figure 3b, Cre: 2.7 crossings, GFP: 5.5 crossings, t(25) = 3.8, P < 0.001).”
BDNF and activity-dependent synaptic modulation. (2003, background): “Bai Lu1”
From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. (2002, background): “BDNF expression in the CA1 region of the hippocampus in rats increases above control values within 30 min of undergoing a contextual conditioning paradigm (Hall et al. 2000).”
Early remodeling of the neocortex upon episodic memory encoding (2014, result): “Consistent with previous data (10, 42), we found that Zif268 expression was significantly increased in the entorhinal cortex (Fig.”
Differential contributions of dorsal hippocampal subregions to memory acquisition and retrieval in contextual fear‐conditioning (2004, background): “Previous literature (Hall et al., 2000) has demonstrated a relationship between contextual fear memory and the expression of LTP-related immediate-early genes (i.”