A computational theory of hippocampal function, and empirical tests of the theory.

By E. T. Rolls, R. Kesner. 2006

663 citations recorded by the source corpus.

Subfields: Economics and Econometrics, Renewable Energy, Sustainability and the Environment

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Economics and Econometrics

1. E. T. Rolls
2. James J. Knierim
3. Joshua P. Neunuebel
4. Catherine E. Myers
5. H. Scharfman
6. R. Kesner

In Renewable Energy, Sustainability and the Environment

1. E. T. Rolls
2. James J. Knierim
3. Joshua P. Neunuebel
4. Catherine E. Myers
5. H. Scharfman
6. R. Kesner

Citations in the corpus

• Spatial firing correlates of physiologically distinct cell types of the rat dentate gyrus (2012, background): “Most theories of DG mnemonic function propose that this region uses a sparse encoding mechanism to subserve pattern separation, in which similar input patterns from the entorhinal cortex are distributed across the large granule cell population to decorrelate the patterns to reduce the probability of”
• Adult-born hippocampal dentate granule cells undergoing maturation modulate learning and memory in the brain (2009, background): “…formation, the DG has recently been proposed to perform a pattern separation role by sparsifying and orthogonizing inputs into the hippocampus in both rodent models and human subjects (Gilbert et al., 2001; Rolls and Kesner, 2006; Leutgeb et al., 2007; McHugh et al., 2007; Bakker et al., 2008).”
• Hippocampal CA3 Output is Crucial for Ripple-Associated Reactivation and Consolidation of Memory (2009, neutral): “This issue is particularly important because, despite the fact that the CA3 recurrent network is thought to be a major storage site for recent HPC memory (Marr, 1971; Rolls and Kesner, 2006), recent work has shown that the alternative direct pathway that bypasses CA3 is necessary for the consolidati”
• The mechanisms for pattern completion and pattern separation in the hippocampus (2013, methodology): “…entorhinal cortex, and parahippocampal structures (areas TF-TH) as well as prefrontal including orbitofrontal cortex (Van Hoesen, 1982; Witter, 1993; Delatour and Witter, 2002; Van Haeften et al., 2003) (see Figure 1), though there are other outputs (Rolls and Kesner, 2006; Rolls, 2014b).”
• Mechanisms of pattern decorrelation by recurrent neuronal circuits (2010, background): “In addition, decorrelated representations are most likely important for robust memory storage by associative networks because correlated representations may be confused or erased by catastrophic interferenc”
• A Role for Hilar Cells in Pattern Separation in the Dentate Gyrus: A Computational Approach (2009, background): “…Norman and O'Reilly, 2003; Meeter et al., 2004), and the basic ideas originally espoused by Marr, Rolls, and their colleagues have generally been validated by subsequent studies of dentate and hippocampal anatomy and physiology (see Rolls and Kesner, 2006; Acsády and Káli, 2007; Kesner, 2007).”
• Pattern separation in the hippocampus through the eyes of computational modeling (2017, background): “…1987; O ’ Reilly & McClelland, 1994; Treves & Rolls, 1992, 1994) as well as experimental studies, using behavioral (Kesner, Lee, & Gilbert, 2004; Rolls & Kesner, 2006), neurophysiological (Leutgeb & Leutgeb, 2007; Leutgeb et al., 2007; McHugh et al., 2007) and functional magnetic resonance…”
• The role of the dentate gyrus, CA3a,b, and CA3c for detecting spatial and environmental novelty (2008, background): “…dentate gyrus; environmental geometry; metric relationships INTRODUCTION It has been proposed that the dentate gyrus (DG) and CA3 interact via the mossy fibers to process spatial information with high spatial resolution (Morris and McNaughton, 1987; Rolls and Treves, 1998; Rolls and Kesner, 2006).”
• Nonrandom Local Circuits in the Dentate Gyrus (2008, background): “Nonrandom hilar circuit motifs, such as reciprocal excitatory/inhibitory connections, likely achieve gain control across many channels simultaneously, generating orthogonal representations of overlapping input patterns (Rolls and Kesner, 2006).”
• The hippocampal indexing theory and episodic memory: Updating the index (2007, background): “We do not intend to relate indexing theory to this vast literature (see O’Reilly and Rudy, 2001; Rolls and Kesner, 2006 for more comprehensive treatments; Morris, 2007).”
• Tracking the Flow of Hippocampal Computation: Pattern Separation, Pattern Completion, and Attractor Dynamics (2015, background): “Relating the neurophysiology to behavioral tests of pattern separation and pattern completion (Rolls & Kesner, 2006; Yassa & Stark, 2011) will help close the loop between theory and experiment and provide key insights into the neural circuit mechanisms underlying the mnemonic functions of the…”
• Structural Plasticity and Hippocampal Function (2010, background): “…from recent studies incorporating a subregional analysis of the hippocampus that suggests a heterogeneous distribution of function within its different subfields (reviewed in Rolls & Kesner 2006) as well as along the septotemporal axis (reviewed in Bannerman et al. 2004, Moser & Moser 1998).”