STAT1-Dependent Innate Immunity to a Norwalk-Like Virus

By Stephanie M. Karst, C. Wobus, Margarita K. Lay, J. Davidson, H. Virgin. Science, 2003

836 citations recorded by the source corpus.

Subfields: Animal Science and Zoology, Cardiology and Cardiovascular Medicine, Infectious Diseases

View Paper: https://www.semanticscholar.org/paper/cbd608362cdcaabc0958b54099d459120bcc7f52

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In Infectious Diseases

1. Marion Koopmans
2. E. Duizer

Citations in the corpus

• Murine Norovirus: a Model System To Study Norovirus Biology and Pathogenesis (2006, methodology): “Of these potential experimental models, the murine norovirus (MNV) is the only norovirus that replicates in cell culture and in a small animal (36, 75).”
• Virus-Plus-Susceptibility Gene Interaction Determines Crohn’s Disease Gene Atg16L1 Phenotypes in Intestine (2010, background): “Hereinafter we will refer to this as a virus-plus-susceptibility gene interaction.”
• Biology and Diseases of Mice (2015, neutral): “Microscopic findings include varying degrees of hepatitis, focal interstitial pneumonia, vasculitis, peritonitis, and pleuritis (Karst et al., 2003; Ward et al., 2006) .”
• Replication of Norovirus in Cell Culture Reveals a Tropism for Dendritic Cells and Macrophages (2004, methodology): “Most noroviruses identified thus far have been associated with gastrointestinal disease in humans, but members of the genus have been found in other species as well (Green et al. 2001; Karst et al. 2003).”
• Norovirus classification and proposed strain nomenclature. (2006, background): “These represent the current five NoV genogroups (GI–GV) as identified in other studies (Fankhauser et al., 2002; Green et al., 1995; Karst et al., 2003; Oliver et al., 2003; Vinje´ and Koopmans, 2000).”
• The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila (2005, background): “The importance of this pathway in the innate control of viral infections in mammals is best demonstrated by genetic studies linking STAT1 deficiencies in mice and humans with increased susceptibility to infectio”
• Laboratory efforts to cultivate noroviruses. (2004, background): “The genus Norovirus is currently subdivided into two genogroups, GGI and GGII, on the basis of sequence homologies of the capsid gene RNA, although subdivision into five genogroups has been proposed recently (Karst et al., 2003).”