Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells.

By K. Jackson, S. Majka, Hongyu Wang, J. Pocius, C. Hartley, M. Majesky, M. Entman, L. Michael, K. Hirschi, Margaret A. Goodell. Journal of Clinical Investigation, 2001

2,069 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/cb144f974b915f165598c409eefb0eab8df647be

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In Cardiology and Cardiovascular Medicine

J. Molkentin

In Genetics

In Molecular Biology

Citations in the corpus

Mesenchymal stem cells: clinical applications and biological characterization. (2004, background): “Enhanced neovascularigenesis has been associated with regeneration of infracted myocardium by bone marrow-derived stem cells (Fuchs et al., 2001; Jackson et al., 2001; Kobayashi et al., 2000; Orlic et al., 2001; Tomita et al., 1999).”
Myogenic specification of side population cells in skeletal muscle (2002, background): “HSCs can differentiate into hepatic cells (Lagasse et al., 2000), cardiac muscle and vascular endothelium (Jackson et al., 2001), and several epithelial cell types (Krause et al., 2001) after transplantation.”
Unchain my heart: the scientific foundations of cardiac repair. (2005, methodology): “by treatment with ROSA26 SP cells (CD34–/lowKit+Sca-1+) that were genetically labeled to express β-gal ubiquitously (75).”
Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain. (2002, background): “For instance, cells infused at the time of bone marrow (BM) transplantation contribute to skeletal muscle myoblasts [1,2] and endothelium [3–7] and acquire hepatic [8-10], biliary duct [8-10], lung, gut, skin epithelia [11], and neuroectoderm [12,13].”
In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion. (2003, background): “After transplantation of bone marrow or enriched hematopoietic stem cells, skeletal lung, gut, and skin epithelia (18), myoblasts (19, 20), cardiac myoblasts (21, 22), endothelium (23, 24), hepatic and biliary duct epithelium (14, 25, 26), or neuroectodermal cells (27, 28) of donor origin can be fou”
Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury (2007, methodology): “We generated double-transgenic MerCreMer-ZEG mice by crossbreeding transgenic B6129-Tg( Myh6-cre/Esr1 )1Jmk/J (hereafter referred to as MerCreMer) mice, in which the cardiomyocyte-specific α-myosin heavy chain ( Myh6 ) promoter drives expression of a 4-OH-tamoxifen-inducible Cre recombinase fusion p”
Systemic Delivery of Bone Marrow–Derived Mesenchymal Stem Cells to the Infarcted Myocardium: Feasibility, Cell Migration, and Body Distribution (2003, methodology): “(3) BM-MSCs are preferentially attracted to and retained in the ischemic tissue but not in the remote or intact myocardium.”
Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction. (2005, background): “Studies with side population cells (7) showed differentiation into multiple cellular types in vivo, but these studies were also performed with mouse cells and did not document any in vivo effects.”