Resveratrol: a review of preclinical studies for human cancer prevention.
By M. Athar, J. H. Back, Xiuwei Tang, K. Kim, L. Kopelovich, D. Bickers, A. Kim. Toxicology and Applied Pharmacology, 2007
762 citations recorded by the source corpus.
Subfields: Geriatrics and Gerontology, Molecular Biology, Pathology and Forensic Medicine
View Paper: https://www.semanticscholar.org/paper/c89bb13e336e2e7b5fb76614ea075ad784999598
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Geriatrics and Gerontology
In Molecular Biology
Citations in the corpus
- Plant polyphenols as dietary antioxidants in human health and disease (2009, background): “The anti-carcinogenic effects of resveratrol appears to be closely associated with its antioxidant activity, and it has been shown to inhibit cyclooxygenase, hydroperoxidase, protein kinase C, Bcl-2 phosphorylation, Akt, focal adhesion kinase, NFκB, matrix metalloprotease-9 and cell cycle regulators”
- Dietary Polyphenols and Their Role in Oxidative Stress-Induced Human Diseases: Insights Into Protective Effects, Antioxidant Potentials and Mechanism(s) of Action (2022, background): “Anti-carcinogenic effects of resveratrol are due to the antioxidant function, which inhibits hydroperoxidase, Akt (PI3K-Akt) signaling pathway, matrix metalloprotease-9, NF-kB, protein kinase C, cyclooxygenase, focal adhesion kinase and Bcl-2 (B cell lymphoma 2) biomarkers/enzymes (Athar et al., 200”
- Cancer Chemoprevention Through Dietary Antioxidants: Progress and Promise (2008, neutral): “Among its various actions, resveratrol has been demonstrated to inhibit cellular survival signaling (21).”
- Natural Phenolic Compounds From Medicinal Herbs and Dietary Plants: Potential Use for Cancer Prevention (2009, result): “These and other in vitro and in vivo studies provide a rationale in support of the use of stilbenes as phytoestrogens to protect against hormone-dependent tumors (51).”
- Repeat Dose Study of the Cancer Chemopreventive Agent Resveratrol in Healthy Volunteers: Safety, Pharmacokinetics and Effect on the Insulin-like Growth Factor Axis (2010, neutral): “The abundance of information on biochemical effects of resveratrol in cultured cells potentially linked to anticarcinogenesis (6) contrasts with a scarcity of studies in humans.”
- Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats (2010, background): “Since then, a broad range of desirable health effects have been ascribed to resveratrol; these include anti-cancer, antiaging, anti-Alzheimer’s, anti-diabetic, anti-viral, neuroprotective, and cardioprotective activities [2–5,7,11,15,20,26,30–35,37].”
- Sirtuins: critical regulators at the crossroads between cancer and aging (2007, background): “Resveratrol is a natural product induced in plants after a variety of stresses and shows potential cancer chemoprotective properties (Athar et al., 2007).”