Bcl10 activates the NF-κB pathway through ubiquitination of NEMO

By Honglin Zhou, I. Wertz, K. O’Rourke, M. Ultsch, S. Seshagiri, M. Eby, Wei Xiao, V. Dixit. Nature, 2004

519 citations recorded by the source corpus.

Subfields: Cancer Research, Immunology

View Paper: https://www.semanticscholar.org/paper/c853ed2fe881d0718916414b49c7e83541549cbe

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. N. Perkins
2. S. Ghosh
3. M. Hayden
4. Ivan Dikic
5. Zhijian J. Chen
6. A. West
7. Shizuo Akira
8. M. Karin

In Immunology

1. N. Perkins
2. S. Ghosh
3. M. Hayden
4. A. West
5. Ivan Dikic
6. Zhijian J. Chen
7. W. Strober
8. A. Kitani

Citations in the corpus

• Signalling pathways and molecular interactions of NOD1 and NOD2 (2006, background): “As shown previously, K63-linked polyubiquitylation is associated with activation of the NF-κB pathwa”
• Macrophage activation by endogenous danger signals (2008, background): “It has been known that K63-linked polyubiquitylation is associated with activation of the NF-κB pathway [38].”
• Ubiquitin signalling in the NF-κB pathway (2005, background): “Two studies have shown that BCL10 and MALT1 induce the Lys 63-linked polyubiquitination of NEMO by UBC13/UEV1A, leading to IKK activatio”