Pre-mRNA splicing: awash in a sea of proteins.

By M. Jurica, Melissa J. Moore. Molecules and Cells, 2003

1,077 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/c8089ef8cdac50477b2e835cf92ae91664776d86

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Citations in the corpus

The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation (2010, background): “930 Molecular Cell 39, 925–938, September 24, 2010 ª2010 Elsevier SF1 is a splicing factor that recognizes the branchpoint sequence and, together with U2AF, promotes binding of U2-snRNP to pre-mRNA, whereas SF3a60 and B00 proteins are integral components of U2-snRNP (Jurica and Moore, 2003).”
Variation in alternative splicing across human tissues (2004, methodology): “For this trans-factor analysis, we obtained a list of 20 splicing factors of the SR, SR-related and hnRNP protein families from proteomic analyses of the human spliceosome [46-48] (see Materials and methods for the list of genes).”
Function of alternative splicing. (2005, neutral): “Mechanism of splice-site selection The mechanism of splicing has been determined in great detail (Jurica and Moore, 2003; Nilsen, 2003).”
Elongation by RNA polymerase II: the short and long of it. (2004, background): “The large spliceosome complex functions to splice premRNAs, and consists of small nuclear ribonucleoprotein particles (snRNPs) and additional proteins such as the serine/arginine-rich (SR) protein family (Jurica and Moore 2003).”
Comparative analysis identifies exonic splicing regulatory sequences--The complex definition of enhancers and silencers. (2006, background): “The splicing reaction is catalyzed by the spliceosome—a complex that contains five small nuclear ribonucleoproteins (snRNPs) and at least 150 additional proteins (Hartmuth et al., 2002; Jurica and Moore, 2003; Nilsen, 2003; Zhou et al., 2002).”
Complexity of the Alternative Splicing Landscape in Plants[C][W][OPEN] (2013, background): “In addition, screens for mutants in various pathways have frequently identified splicing factors as modulators of functional proteins, indicating that these pathways are regulated via differential splicing (Lee et al., 2006; Monaghan et al., 2009; Sugliani et al., 2010; Fouquet et al., 2011; Koncz…”
The spliceosome: design principles of a dynamic RNP machine. (2009, background): “…in coupling the splicing machinery Cell 136, 701–718, February 20, 2009 ª2009 Elsevier Inc. 707 to other molecular machines in the cell such as those responsible for transcription, 30-end processing, or quality control of spliced mRNPs (reviewed in Jurica and Moore, 2003; Maniatis and Reed, 2002).”
Splicing regulation: from a parts list of regulatory elements to an integrated splicing code. (2008, background): “Containing more than 100 core proteins and five small nuclear RNAs (snRNAs U1, U2, U4, U5, and U6), spliceosomes may be the most complex machines in the cell (Zhou et al. 2002; Jurica and Moore 2003; Nilsen 2003).”
Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing. (2007, methodology): “As the U2 snRNP is a component of the prespliceosome (Complex A [Jurica and Moore, 2003]), we tested the H3K4me3 eluate for additional proteins involved in prespliceosome formation, including SR proteins, the U1 snRNP-specific protein U1-70K, and U2 snRNP-specific proteins.”
Mechanisms and Regulation of Alternative Pre-mRNA Splicing (2015, background): “Collectively, these studies have provided an appreciation for the large, diverse, and dynamic protein composition of the spliceosome (>200 proteins in metazoans; ∼100 in yeast) (53) and also of how the protein composition of the spliceosome dynamically changes as the assembly and subsequent catalyti”
The Arabidopsis Cold-Responsive Transcriptome and Its Regulation by ICE1w⃞ (2005, background): “These genes are known to be involved in RNA metabolism, including splicing, ribosome biogenesis, mRNA export, translational regulation, and RNA degradation (Farina and Singer, 2002; Jurica and Moore, 2003; Rocak and Linder, 2004).”