Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing.

By R. Sims, S. Millhouse, Chi-Fu Chen, B. Lewis, H. Erdjument‐Bromage, Paul Tempst, J. Manley, D. Reinberg. Molecules and Cells, 2007

614 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/66667329b0a43c2e4cb89e1a7ca9b24135b849d0

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In Molecular Biology

1. D. Reinberg
2. R. Margueron
3. J. Manley
4. K. Sarma
5. E. Nestler
6. Mo Chen
7. Li Shen
8. Xiaochuan Liu

Citations in the corpus

• diffReps: Detecting Differential Chromatin Modification Sites from ChIP-seq Data with Biological Replicates (2013, background): “Previously, people have reported the histone mark’s association with splicing [15].”
• Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches (2009, background): “In addition, there has been accumulating evidence showing the coupling of RNA transcription to splicing regulatio”
• Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes (2012, background): “To confirm this hypothesis, we assessed the genome-wide binding pattern upon b-glucan training of H3K4me3 and H3K27me3, two histone modifications associated, among others, with the epigenetic regulation of immune-related genes (Barski et al., 2007; Buratowski and Kim, 2010; Foster et al., 2007; Ishi”
• Pre-mRNA processing reaches back to transcription and ahead to translation. (2009, neutral): “However, it has become evident that pre-mRNA processing plays a critical role (Manley, 2002; Orphanides and Reinberg, 2002; Sims et al., 2007).”
• Epigenetics in alternative pre-mRNA splicing (2011, neutral): “, 2006), or through specific recruitment of splicing factors via adaptor complexes to weak RNA-binding sites (Luco et al., 2010; Sims et al., 2007; Gunderson and Johnson, 2009; Piacentini et al., 2009).”
• Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms (2008, methodology): “We then probed for changes in chromatin structure as a function of the presence of PRC2-Ezh1 and SAM using sucrose density gradient centrifugation and electron microscopy (EM) (Sims et al., 2007).”
• Mechanisms and consequences of alternative polyadenylation (2011, neutral): “The latter case would be analogous to the mechanism by which recognition of H3K4me3 by CHD1 functions, at the 50 ends of actively transcribed genes, to recruit core spliceosomal components, therefore facilitating the efficiency of pre-mRNA splicing (Sims et al., 2007).”