Sleep deprivation and activation of morning levels of cellular and genomic markers of inflammation.

By Michael R. Irwin, Minge Wang, Capella O Campomayor, Alicia Collado-Hidalgo, S. Cole. Archives of Internal Medicine, 2006

814 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Experimental and Cognitive Psychology, Physiology

View Paper: https://www.semanticscholar.org/paper/c7aeebb7fe77c5eea62c05271a1fed073d51ebda

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Citations in the corpus

Depressive disorders and immunity: 20 years of progress and discovery. (2007, background): “Moreover, depressed patients with more severe sleep disturbance may be at greater risk for elevated levels of IL-6 and other proinflammatory markers, because sleep loss has been shown to induce acute increases in cellular and genomic markers of inflammation (Irwin et al., 2006).”
Why Sleep Is Important for Health: A Psychoneuroimmunology Perspective (2014, background): “Partial-night sleep deprivation induces an increase in TLR-4-stimulated production of IL-6 and TNF, which is especially prominent in women who show sustained elevations ADRB2 TLR4 Circulation SNS nerve fibers Cardiovascular disease Major depressive disorder Cancer NF-κB Expression of proinflammatory”
The Sleep-Immune Crosstalk in Health and Disease (2019, background): “Following sleep deprivation in the first night half, TNF production in monocytes and TNF mRNA were shown to be increased in the morning (256, 262, 264).”
Cardiovascular, Inflammatory and Metabolic Consequences of Sleep Deprivation (2009, background): “Nonetheless, following a single night of sleep reduced by 50%, Irwin and colleagues (64) showed an increase in monocyte production of IL-6 and TNF-a messenger RNA.”
Reciprocal regulation of the neural and innate immune systems (2011, background): “Wake–sleep cycles have emerged as prominent regulators of inflammatory biology, with experimental sleep restriction studies showing upregulated leukocyte expression of pro-inflammatory cytokine genes and increased NF-κB activit”
Social regulation of gene expression in human leukocytes (2007, background): “Bioinformatic analyses of differentially expressing promoters [41,42] test the specific hypotheses that immune cells from high-lonely individuals show in vivo, under basal physiological conditions: 1.”
Sleep Disturbance, Sleep Duration, and Inflammation: A Systematic Review and Meta-Analysis of Cohort Studies and Experimental Sleep Deprivation (2015, background): “org/journal cascade, NF-κB (111), which, in turn, drives effects on transcriptome dynamics with an upregulation of a gene ensemble that includes the master circadian regulator, several immediate early genes marking cellular signal transduction, and multiple inflammatory response genes (122).”