Cardiovascular, Inflammatory and Metabolic Consequences of Sleep Deprivation
By J. Mullington, M. Haack, M. Toth, J. Serrador, H. Meier-Ewert. Progress in cardiovascular diseases, 2009
806 citations recorded by the source corpus.
That insufficient sleep is associated with poor attention and performance deficits is becoming widely recognized. Fewer people are aware that chronic sleep complaints in epidemiological studies have also been associated with an increase in overall mortality and morbidity. This article summarizes findings of known effects of insufficient sleep on cardiovascular risk factors including blood pressure, glucose metabolism, hormonal regulation and inflammation with particular emphasis on experimental sleep loss, using models of total and partial sleep deprivation, in healthy individuals who normally sleep in the range of 7-8 hours and have no sleep disorders. These studies show that insufficient sleep alters established cardiovascular risk factors in a direction that is known to increase the risk of cardiac morbidity.
Subfields: Experimental and Cognitive Psychology, Public Health, Environmental and Occupational Health
View Paper: https://www.semanticscholar.org/paper/4f9072384fe8432f5b139f6c8ee9d19d2d783386
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Experimental and Cognitive Psychology
In Public Health, Environmental and Occupational Health
Citations in the corpus
- An fMRI Study of Cytokine-Induced Depressed Mood and Social Pain: The Role of Sex Differences (2009, background): “Indeed, we have previously found that females, but not males, show a marked activation of NF-κ-B in response to an acute stressor (sleep loss; Irwin et al., 2008), which is known to increase proinflammatory cytokines (Mullington et al., 2009).”
- Sleep and immune function (2011, background): “Moreover, the increases in inflammatory markers after prolonged sleep loss are usually in the same range as that observed in individuals at risk for developing cardiovascular disease in the future [87, 88].”
- Why Sleep Is Important for Health: A Psychoneuroimmunology Perspective (2014, background): “In addition, sleep complaints—possibly through effects on inflammation—contribute to cardiovascular disease risk (Mullington et al. 2009).”
- Loneliness Matters: A Theoretical and Empirical Review of Consequences and Mechanisms (2010, neutral): “Experimental sleep deprivation has adverse effects on cardiovascular functioning, inflammatory status, and metabolic risk factors [44].”